Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6423 | (+/-)-Forbesione |
| 1. Forbesione has antitumor effects, it combined with 5-FU strongly induced apoptosis in Ham-1 cells. 2. Forbesione exhibits anti-HIV-1 activity. | |
| BCN7937 | Daphnodorin B |
| 1. Daphnodorin B shows inhibitory effects of human chymase. 2. Daphnodorin B inhibited tumor growth and metastasis by protecting host immunocyte viability and proliferation potential, and selectively inhibiting tumor cell proliferation. 3. Daphnodorin B has antifungal, antimitotic and anti-HIV-1 activity, it induced morphological deformation of P. oryzae mycelia with MMDC values of 73.7 +/- 1.6 microM, it showed moderate activity against microtubule polymerization with IC50 values of 142 +/- 2 microM in vitro, and it moderately active against HIV-1 in vitro. | |
| BCN7939 | Curculigoside B |
| 1. Curculigoside B has antiosteoporotic activity, it can decrease area of bone resorption pit, osteoclastic formation and TRAP activity. 2. Curculigoside B shows potent antioxidative activity. | |
| BCN7940 | Episappanol |
| 1. Episappanol has anti-inflammatory activity , it can significantly inhibit the secretion of the pro-inflammatory cytokines interleukin (IL-6) and tumor necrosis factor-alpha (TNF-α). | |
| BCN7942 | Sappanone B |
| 1. Sappanone B exhibits moderate to weak activity against methicillin-susceptible S. aureus (MSSA) and other standard strains by MICs/MBCs ranged from 32/64 to >1024/>1024 ug/ml. 2. Sappanone B has vasorelaxation effects, it exhibits an acute relaxation either in endothelium-intact or endothelium-denuded rings in a concentration-dependent manner. | |
| BCN7943 | 2,3-Dihydro-3-methoxywithaferin A |
| 1. 2,3-Dihydro-3-methoxywithaferin A is a natural withanolide , is cytotoxic to human cancer cells, and is a candidate anticancer natural compound. 2. 2,3-Dihydro-3β-methoxy withaferin A protects normal cells against stress . | |
| BCN7944 | Tamgermanetin |
| 1. Tamgermanetin demonstrates potential cytotoxic effect against three different tumor cell lines, namely liver (Huh-7), breast (MCF-7) and prostate (PC-3). | |
| BCN5320 | N-p-trans-Coumaroyltyramine |
| Paprazine may have cytotoxic activity. | |
