Home >> Hot Products

Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No.	Product Name
BCN7906	Uralsaponin C
1. Uralsaponin C shows the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 > 100 μmol/L.
BCN5945	Isoliquiritin
1. Isoliquiritoside has antioxidant activity,remarkable anti-tumor and anti-HIV effects. 2. Isoliquiritoside shows strong inhibition against pancreatic lipase ( IC50 of 37.6 uM ).
BCN7914	trans-Cinnamic anhydride
1. trans-Cinnamic anhydride is a acylating agent.
BCN7916	Isophysalin A
1. Isophysalin A exhibits anti-inflammatory activitiy. 2. Isophysalin A exhibits conjugating abilities with glutathione and also shows significant nitric oxide (NO) production inhibiting activities.
BCN7917	Physalin H
1. Physalin H shows strong quinone reductase induction activity with IR (Induction ratio, QR induction activity) value of 3.74±0.02. 2. Physalin H is an Hh signaling inhibitor blocks GLI1-DNA-complex formation. 3. Physalin H shows immunosuppressive effects on T cells both in vitro and in vivo, and the immunosuppressive activity might be attributed to the suppression of T cell activation and proliferation, the modulation of Th1/Th2 cytokine balance and the induction of HO-1 in T cells. 4. Physalin H shows significant in vitro leishmanicidal activities (0.92-19.4 microg/ml) against promastigotes of Leishmania major. 5. Physalin H shows cytotoxic activity against a panel of human and murine cancer cell lines.
BCN7919	Physalin D
1. Physalin D shows antimalarial activity. 2. Physalin D displays considerable cytotoxicity against several cancer cell lines. 3. Physalin D exhibits a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H(37)Rv strain of 32 microg/mL. 4. Physalin D presents antinociceptive properties associated with central.
BCN7920	Physalin A
1. Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling. 2. Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells. 3. Physalin A inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and downregulation of androgen receptor expression.
BCN7921	Physalin B
1. Physalin B shows potent anti-Trypanosoma cruzi activity. 2. Physalin B shows antimalarial activity. 3. Physalin B can inhibit the growth of several human leukemia cells. 4. Physalin B has the potential to be developed as an effective chemotherapeutic lead compound for the treatment of malignant melanoma. 5. Physalin B inhibits Rhodnius prolixus hemocyte phagocytosis and microaggregation by the activation of endogenous PAF-acetyl hydrolase activities. 6. Physalin B exhibits a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H(37)Rv strain of 32 microg/mL. 7. Physalin B inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and downregulation of androgen receptor expression. 8. Physalin B presents antinociceptive properties associated with central.