Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1761 - 1768 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6165 | TC-G 1004 |
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Potent antagonist of adenosine A2A receptors; displays >100-fold selectivity for A2A over A1 receptors (Ki values are 0.44 and 85 nM respectively). Potentiates L-DOPA-induced rotational behavior in 6-OHDA-lesioned rats.
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| BCC6166 | SR 1664 |
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Antidiabetic agent; binds to PPAR<span class='symbol'>γ</span> and potently inhibits Cdk5-mediated PPAR<span class='symbol'>γ</span> phosphorylation (IC<sub>50</sub> = 80 nM; K<sub>i</sub> = 28.67 nM) without exhibiting PPAR<span class='symbol'>γ</span> agonist activity. Does not inhibit Cdk5-dependent phosphorylation of Rb. Reduces fasting insulin levels and improves insulin sensitivity in a mouse model of diabetes.
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| BCC6167 | Ocinaplon |
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Modulator of GABA<sub>A</sub> receptors. Displays modest selectivity for GABA<sub>A</sub> α<sub>1</sub> receptors; displays partial agonist activity at <span class='symbol'>α</span>2-, <span class='symbol'>α</span>3- and <span class='symbol'>α</span>5-containing receptors. Exhibits anxiolytic activity.
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| BCC6168 | Psilocin |
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Non-selective serotonin receptor agonist. Active metabolite of psilocybin; hallucinogen.
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| BCC6169 | TP 003 |
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Functionally selective GABA<sub>A</sub> receptor (<span class='symbol'>α</span>3 subtype) partial agonist. Exhibits affinity for the benzodiazepine binding site on human GABA<sub>A</sub> receptors. Potentiates the GABA (<span class='symbol'>α</span>3 subtype) response selectively with high efficacy. Produces anxiolytic-like effects in rodent behavioral models of anxiety.
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| BCC6170 | MK 0343 |
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Subtype-selective GABAA partial agonist (Ki values are 0.21, 0.22, 0.23 and 0.40 for α3, α1, α5 and α2 respectively); occupies the benzodiazepine site of GABAA receptors. Displays greater agonist efficacy at α3 compared to α1. Exhibits anxiolytic and non-sedating properties in rodent models. Brain penetrant.
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| BCC6171 | ADX 10059 hydrochloride |
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Reported to be a negative allosteric modulator at the mGlu<sub>5</sub> receptor. Analog of MPEP.
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| BCC6172 | PF 945863 |
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Macrolide antibiotic. Active against multidrug resistant respiratory tract bacterial strains. Does not have the hepatotoxic side effects associated with telithromycin. Orally active.
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