Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3732 | 3-Galloylquinic acid |
| 1. L-theanine- and theogallin(3-Galloylquinic acid )-enriched decaffeinated green tea extract are able to change the physiological pattern of electrical hippocampus activity in a concentration dependent manner (EC50=3mg/L), they can improve cognition at concomitant mental relaxation in man. 2. Theogallin, its derivatives, its metabolite quinic acid, the derivatives thereof, its metabolites or the pharmaceutically acceptable salts of said substances can be used for producing a drug for use in the prophylaxis or treatment of neurological and psychiatric diseases of the central nervous system, especially of dementia such as Alzheimer's disease or Parkinson's disease, of depressions and concentration disorders such as attention deficit hyperactivity disorder. 3. Theogallin has scavenging radical activity. | |
| BCN3733 | 4-Galloylquinic acid |
| 1. 4-Galloylquinic acid shows some antioxidative activity. | |
| BCN3734 | Digitonin |
| 1. Digitonin alone and together with the set of secondary metabolites (SM) , can mediate MDR reversal in cancer cells. 2. Digitonin solubilizes mitochondrial membrane, breaks the integrity of the respiratory chain and releases two mobile redox-active components: coenzyme Q (CoQ) and cytochrome c (cyt c). | |
| BCN3735 | Sappanol |
| 1. Sappanol inhibits lipid peroxidation in a concentration-dependent manner, can significantly attenuated H2O2-induced retinal death, can be potential antioxidant treatment for retinal diseases. | |
| BCN3736 | 3-Deoxysappanchalcone |
| 1. 3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level. 2. 3-Deoxysappanchalcone has anti-inflammatory effects, is a valuable compound for modulating inflammatory conditions. 3. 3-Deoxysappanchalcone has anti-influenza virus activity, the mechanism involved anti-apoptosis and anti-inflammation activities in vitro. 4. 3-Deoxysappanchalcone has inhibitory activity on MMP-9 expression and production in TNF-α-treated cells, is mediated by the suppression of AP-1 and NF-κB activation. | |
| BCN3738 | Eriosemation |
| 1. Eriosemation significant androgen receptor (AR) inhibition activity, suggests that it could be a promising candidate for further evaluation for prostate cancer prevention or management. | |
| BCN3739 | Peroxydehydrotumulosic acid |
| 1. 5alpha,8alpha-Peroxydehydrotumulosic acid exhibits inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. | |
| BCN3740 | Dehydrotumulosic acid |
| 1. Dehydrotumulosic acid shows anti-inflammatory activity. | |
