Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1793 - 1800 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6198 | A 804598 |
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Potent, competitive P2X<sub>7</sub> receptor antagonist (IC<sub>50</sub> values are 8.9, 9.9 and 10.9 nM for mouse, rat and human P2X<sub>7</sub> receptors respectively). Selective for P2X<sub>7</sub> receptors (IC<sub>50</sub> > 5-10 <span class='symbol'>μ</span>M for a wide array of cell surface receptors and ion channels). Binds with high affinity (K<sub>i app</sub> = 2.4 nM for rat P2X<sub>7</sub> receptors).
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| BCC6199 | Cardionogen 1 |
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Wnt signaling modulator. Potently inhibits Wnt/<span class='symbol'>β</span>-catenin-dependent transcription in murine ES cells (EC<sub>50</sub> = 23 nM) and zebrafish embryos. Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation.
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| BCC6200 | A 844606 |
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Selective <span class='symbol'>α</span>7 nicotinic acetylcholine receptor (nAChR) partial agonist (EC<sub>50</sub> values are 1.4 and 2.2 <span class='symbol'>μ</span>M at human and rat receptors respectively). Displays no measurable effect on <span class='symbol'>α</span>4<span class='symbol'>β</span>2 nAChRs. Stimulates <span class='symbol'>α</span>7 nAChR-induced ERK1/2 phosphorylation in PC12 cells.
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| BCC6201 | GPBAR-A |
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GPBA receptor agonist. Upregulates GLP-1 secretion from intestinal cultures. Increases MQAE-fluorescence suggesting a decrease in intracellular chloride concentration in gallbladder epithelial cells.
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| BCC6202 | DV 7028 hydrochloride |
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Selective 5-HT2A receptor antagonist (Ki = 22 nM for at 5-HT2 receptors). Exhibits no affinity for 5-HT1A, 5-HT1B or 5-HT1D receptors. Inhibits collagen-induced serotonin secretion and platelet aggregation; displays no effect on serotonin uptake by platelets. Shown to inhibit arterial thrombus formation, but not venous thrombosis, in rat models.
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| BCC6203 | A 484954 |
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Inhibitor of eukaryotic elongation factor-2 (eEF-2) kinase (IC<sub>50</sub> = 0.28 <span class='symbol'>μ</span>M in enzymatic assay). Reduces eEF-2 phosphorylation with little effect on cancer cell growth.
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| BCC6204 | 1-Deazaadenosine |
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Inhibitor of adenosine deaminase (K<sub>i</sub> = 0.66 <span class='symbol'>μ</span>M). Demonstrates antitumor activity in a range of leukemia cell lines.
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| BCC6205 | DQP 1105 |
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Noncompetitive NMDA receptor antagonist; displays over 50-fold selectivity for GluN2D- and GluN2C-containing receptors over GluN2B-, GluK2-, GluA1- and GluN2A-containing receptors (IC<sub>50</sub> values are 2.7, 8.5, 121, 153, 198 and 206 <span class='symbol'>μ</span>M, respectively). Reduces frequency of channel opening.
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