Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3787 | Nothofagin |
| 1. Nothofagin has antioxidant activity. 2. Nothofagin and Aspalathin may have significant benefits in the treatment of diabetic complications. 3. Nothofagin and Aspalathin possess antithrombotic activity and offers a basis for development of a novel anticoagulant. 4. Nothofagin and Aspalathin possess anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. 5. Nothofagin and Aspalathin have potential to as an anti-sendothelial cell protein C receptor shedding reagent against phorbol-12-myristate 13-acetate and cecal ligation and puncture -mediated endothelial cell protein C receptor shedding. | |
| BCN7875 | Hexanorcucurbitacin D |
| 1. Hexanorcucurbitacin D is a weak agonist acting at the ecdysteroid receptor. | |
| BCN7877 | Cucurbitacin R |
| 1. Cucurbitacin R, a natural anti-inflammatory product, has been shown to exhibit activity against both adjuvant-induced arthritis and delayed-type hypersensitivity reactions induced by various agents. 2. Cucurbitacin R has the potential to be a new immunosuppressive agent with antiproliferative effects through the inhibition of the NFAT with anti-inflammatory activity in DTH reactions. 3. Cucurbitacin R reduces the inflammation and bone damage associated with adjuvant arthritis in lewis rats by suppression of tumor necrosis factor-alpha in T lymphocytes and macrophages. 4. Cucurbitacin R can exert antitumorigenic activity in the absence of activated STAT3. | |
| BCN7881 | Toonaciliatin M |
| 1. Toonaciliatin M shows moderate antifungal activity against Trichophyton rubrum (MIC = 12.5 microg/mL). 2. Toonaciliatin M shows moderate inhibitory activity against lipopolysaccharide-induced nitric oxide production in RAW264.7 cells. | |
| BCN7884 | Psoracorylifol B |
| 1. Psoracorylifol B has antimicrobial activity. | |
| BCN7886 | (2R,3S)-Dihydrodehydroconiferyl alcohol |
| 1. (2R,3S)-Dihydrodehydroconiferyl alcohol can induce neurite outgrowth and enhance NGF-induced neurite outgrowth from PC12 cells by amplifying up-stream steps such as MAPK and PKC. | |
| BCN7891 | Drynachromoside A |
| 1. Drynachromoside A exhibits the biochemical effects on the proliferation of MC3T3-E1 cells. | |
| BCN7894 | Licoricesaponin E2 |
| 1. Licoricesaponin E2 displayed the inhibition on the growth of cancer cells with IC50 at 18.3-41.6 umol/L, it could significantly increase the cytotoxic activity after hydrolysis. | |
