Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3687 | Flavanthrin |
| 1. Flavanthrin shows significant cytotoxicity against MCF-7, NCI-H460, and SF-268 cell lines. | |
| BCN3688 | Thunalbene |
| 1. Thunalbene shows weak inhibitory activities without cytotoxicity on the production of nitric oxide (NO) which is an important inflammatory mediator. | |
| BCN3689 | Lusianthridin |
| 1. Lusianthridin shows appreciable cytotoxicity against human lung cancer cell lines. 2. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. | |
| BCN3691 | Dihydroevocarpine |
| 1. Dihydroevocarpine and 1-methyl-2-undecyl-4-quinolone are moderate modulators of p-glycoprotein (p-gp) activity. 2. Dihydroevocarpine shows more potent inhibitory effects against MAO-B compared to MAO-A. 3. Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. | |
| BCN3692 | Sanggenol L |
| 1. Sanggenol L induces apoptosis via caspase activation and inhibition of NF-κB/IκBα phosphorylation as a potent chemotherapeutic agent for ovarian cancers. 2. Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF). | |
| BCN3693 | Mulberrofuran G |
| 1. Mulberrofuran G shows moderate activity, inhibits hepatitis B virus (HBV) DNA replication with the IC(50) value of 3.99 μM. | |
| BCN3694 | Neoprocurcumenol |
| 1. Neoprocurcumenol exerts significant toxicity on mosquito larvae . | |
| BCN3697 | Benzyl 2,6-dimethoxybenzoate |
| 1. Benzyl 2,6-dimethoxybenzoate shows significant analgesic effects. 2. Benzyl 2,6-dimethoxybenzoate induces a concentration-dependent inhibition of the spontaneous contractions of the guinea-pig ileum with IC50 values ranging from 1.49 to 4.96 microM. 3. Benzyl 2,6-dimethoxybenzoate shows antimicrobial activity against several bacteria (S. aureus, E. coli, P. aeruginosa, and B. subtilis) and fungi (C. albicans and T. mentagrophytes). | |
