Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1737 - 1744 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6141 | VU 0360172 hydrochloride |
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Positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM). Selective for mGlu5; displays no significant activity at mGlu1, mGlu2 or mGlu4 receptors. Exhibits antipsychotic-like activity in a rodent model. Also reduces spontaneous spike and wave discharges without affecting motor behaviour in a rat model of absence epilepsy.
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| BCC6142 | JW 480 |
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Potent and selective inhibitor of the serine hydrolase enzyme KIAA1363 (AADACL1) (IC50 = 20 nM in mouse brain). Impairs migration, invasion, survival and tumor growth of prostate cancer cell lines in vivo. Reduces monoalkylglycerol ether (MAGE) levels.
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| BCC6143 | AR-M 1000390 hydrochloride |
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Non-peptidic, low-internalizing <span class='symbol'>δ</span>-selective opioid receptor agonist; derivative of SNC 80. Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain penetrant following systemic administration.
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| BCC6144 | TC-C 14G |
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Potent, high affinity CB1 receptor inverse agonist (EC50 = 11 nM in cAMP assay; Ki = 4 nM). Demonstrates high efficacy in a hypothermia assay (ID50 = 5 mg/kg) in vivo.
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| BCC6145 | Ro 67-7476 |
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Positive allosteric modulator of mGlu1 receptors. Potentiates glutamate-induced calcium release (EC50 = 60.1 nM at rat mGluR1a). Displays no activity at human mGlu1 receptors.
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| BCC6146 | TC-G 24 |
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Potent GSK-3<span class='symbol'>β</span> inhibitor (IC<sub>50</sub> = 17 nM); displays selectivity for GSK-3<span class='symbol'>β</span> over CDK2 (22% inhibition at 10 <span class='symbol'>μ</span>M). Increases liver glycogen reserves in rodents. Brain penetrant.
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| BCC6147 | TC-F 2 |
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Potent, reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC<sub>50</sub> values are 28 and 100 nM for human and rat FAAH respectively). Noncovalent inhibitor; displays selectivity for FAAH over cannabinoid-related targets (IC<sub>50</sub> > 20 <span class='symbol'>μ</span>M for CB<sub>1</sub>, CB<sub>2</sub> and TRPV1). Active <em>in vivo</em>.
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| BCC6148 | PF 5081090 |
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Potent antibacterial agent which disrupts lipid bilayer synthesis through inhibition of LpxC (IC50 = 1.1 nM in Pseudomonas aeruginosa); effective against a range of gram negative bacteria.
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