Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3603 | Butyraxanthone B |
| 1. Butyraxanthone B exhibits good antiplasmodial activity. | |
| BCN3604 | Garcinone E |
| 1. Garcinone E is active constituents in the anticomplement assay used. 2. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. 3. Garcinone E has potent cytotoxic effect on all hepatocellular carcinomas cell lines as well as on the other gastric and lung cancer cell lines included in the screen, may be potentially useful for the treatment of certain types of cancer. | |
| BCN3606 | (-)-beta-Peltatin |
| 1. (-)-beta-Peltatin has antimitotic, and antineoplastic activities. | |
| BCN3607 | (-)-beta-Peltatin-5-O-beta-D-glucopyranoside |
| 1. beta-Peltatin-5-O-beta-D-glucopyranoside provides potent cancer cell growth inhibitory activity (GI50 0.1 to <0.03 ug/mL) against a panel of six human cancer cell lines and one murine cancer cell line. 2. beta-Peltatin-5-O-beta-D-glucopyranoside shows modest antiproliferative activities against the A2780 ovarian cancer cell line, with the IC50 value of 4.9 ± 0.1 uM. | |
| BCN3610 | 3-Hydroxybakuchiol |
| 3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation.3-Hydroxybakuchiol has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells. | |
| BCN3613 | 6-Methoxyluteolin |
| 1. 6-Methoxyluteolin has antioxidant activity. 2. 6-Methoxyluteolin is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. | |
| BCN1571 | Methyl 4-Hydroxyphenylacetate |
| 1. Methyl 4-Hydroxyphenylacetate has potent inhibitory activity against tobacco mosaic virus (TMV). | |
| BCN3618 | (±)-Marmesin |
| Marmesin has hepatoprotective potential; it also has cytotoxic with a 50% lethal dose of less than 0.5 micrograms/ml, is not as mutagenic or potentially carcinogenic as are AFB1, imperatorin, or MOP with BL activation. | |
