Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3509 | Britannilactone |
| 1. Britannilactone significantly reduces melanin production in a dose-dependent manner with the IC50 value of 15.5 uM. | |
| BCN3510 | Neobritannilactone B |
| 1. Neobritannilactone B has cytotoxic activity. | |
| BCN3512 | RA VII |
| 1. RA VII is an antitumour agent, shows cytotoxic activity against P-388 cells. 2. RA VII causes the conformational change of F-actin and the stabilization of actin filaments to induce G2 arrest. | |
| BCN3513 | RA-V |
| 1. RA-V is an potential anti-angiogenic agent, exhibits anti-angiogenic activities in HUVEC and HMEC-1 cell lines with changes in function of these endothelial cells. 2. RA-V has anti-cancer activity, is a potential anti-metastatic agent in breast cancer, and likely acts via PI3K/AKT and NF-κB signaling pathways in both ER-positive and ER-negative breast cancer cells. | |
| BCN3514 | RA-XI |
| 1. RA-XI shows potent antitumor activity against P-388. | |
| BCN3515 | Rhapontigenin |
| Rhapontigenin has antioxidative, antihyperlipidemic, antifungal and anticancer activities. Rhapontigenin inhibits HIF-1α accumulation and angiogenesis in PC-3 prostate cancer cells, suppresses breast cancer cell migration and invasion, which is involved in inhibiting the PI3K-dependent Rac1 signaling pathway. Rhapontigenin exhibits dose-dependent inhibition of tyrosinase activity and melanin synthesis in B16F10 melanoma cells. | |
| BCN3516 | Rosamultic acid |
| 1. Rosamultic acid is a class of triterpenes with α-glucosidase inhibitory activity. | |
| BCN3517 | 1beta-Hydroxyeuscaphic acid |
| 1.1beta-Hydroxyeuscaphic acid has significant hepatoprotective activity by lowering the leakage of intracellular enzymes, reducing the oxidation of proteins and decreasing the incidence of apoptosis. | |
