Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1673 - 1680 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6075 | EHT 1864 |
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Inhibitor of Rac family GTPases. Blocks activation by direct binding to Rac1, Rac1b, Rac2 and Rac3 (K<sub>D</sub> values are 40, 50, 60 and 250 nM respectively). Inhibits Rac, Ras and Tiam-induced growth transformation of NIH-3T3 fibroblasts. Reduces <span class='symbol'>β</span>-amyloid peptide production <em>in vivo</em>.
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| BCC6076 | BIO-acetoxime |
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Selective GSK-3<span class='symbol'>α</span>/<span class='symbol'>β</span> inhibitor (IC<sub>50</sub> values are 0.01, 2.4, 4.3 and 63 <span class='symbol'>μ</span>M for GSK-3<span class='symbol'>α</span>/<span class='symbol'>β</span>, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling and inhibits CD8+ T cell effector differentiation.
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| BCC6077 | Kisspeptin 234 |
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kisspeptin receptor (KISS1, GPR54) antagonist; kisspeptin-10 analog. Inhibits kisspeptin-10 stimulation of inositol phosphate (IP) (IC<sub>50</sub> = 7 nM) and release of gonadotrophin-releasing hormone (GnRH).
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| BCC6078 | (E)-FeCP-oxindole |
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Selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC<sub>50</sub> = 214 nM). Displays anticancer activity (IC<sub>50</sub>< 1 <span class='symbol'>μ</span>M against B16 murine melanoma lines). Does not significantly inhibit VEGFR1 or PDGFRa or b at a concentration of 10<span class='symbol'>μ</span>M. Geometric isomer of (<em>Z</em>)-FeCP-oxindole.
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| BCC6079 | (Z)-FeCP-oxindole |
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Selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC<sub>50</sub> = 220 nM). Displays anticancer activity (IC<sub>50</sub>< 1 <span class='symbol'>μ</span>M against B16 murine melanoma lines). Does not significantly inhibit VEGFR1 or PDGFRa or b at a concentration of 10<span class='symbol'>μ</span>M. Geometric isomer of (<em>E</em>)-FeCP-oxindole.
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| BCC6080 | TCS 2314 |
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Integrin very late antigen-4 (VLA-4; <span class='symbol'>α</span><sub>4</sub><span class='symbol'>β</span><sub>1</sub>) antagonist (IC<sub>50</sub> = 4.4 nM). Blocks the activation of inflammatory cells.
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| BCC6081 | S 18986 |
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Positive allosteric modulator of AMPA receptors. Exhibits cognitive enhancing properties in rodent behavioral models. Brain penetrant.
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| BCC6082 | HX 531 |
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Potent RXR antagonist (IC50 = 18 nM). Promotes white and brown pre-adipocyte differentiation into white adipocytes. Also inhibits bexarotene-induced brown adipogenic reprogramming of myoblasts.
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