Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1681 - 1688 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6083 | HX 630 |
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RXR agonist. Acts as a retinoid synergist; enhances the potency of AM 80 in a HL-60 cell differentiation assay.
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| BCC6084 | AMG 548 |
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Potent and selective inhibitor of p38<span class='symbol'>α</span> (K<sub>i</sub> values are 0.5, 3.6, 2600 and 4100 nM for p38<span class='symbol'>α</span>, p38<span class='symbol'>β</span>, p38<span class='symbol'>γ</span> and p38<span class='symbol'>δ</span> respectively). Displays >1000-fold selectivity against 36 other kinases; inhibits whole blood LPS-stimulated TNF<span class='symbol'>α</span> (IC<sub>50</sub> = 3 nM)<strong></strong>. Efficacious in acute and chronic models of arthritis.
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| BCC6085 | Orphanin FQ (1-11) |
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Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL<sub>1</sub>/KOR-3 receptor (K<sub>i</sub> = 55 nM); displays no affinity for opioid receptors, including <span class='symbol'>μ</span>, <span class='symbol'>δ</span>, <span class='symbol'>κ</span><sub>1</sub> and <span class='symbol'>κ</span><sub>3</sub> receptors (K<sub>i</sub> >1000 nM). Displays analgesic properties in CD-1 mice.
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| BCC6086 | RWJ 52353 |
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Agonist of the <span class='symbol'>α</span><sub>2D</sub> adrenergic receptor (K<sub>i</sub> values are 1.5, 254, 443 and 621 nM for <span class='symbol'>α</span><sub>2D</sub>, <span class='symbol'>α</span><sub>2A</sub>, <span class='symbol'>α</span>1 and <span class='symbol'>α</span><sub>2B</sub> adrenergic receptors respectively).
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| BCC6087 | TCS 1105 |
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GABA<sub>A</sub> benzodiazepine receptor (BZR) ligand. Acts as an agonist at <span class='symbol'>α</span><sub>2</sub> and antagonist at <span class='symbol'>α</span><sub>1</sub> benzodiazepine receptors (K<sub>i</sub> values are 118 and 245 nM respectively). Anxiolytic agent lacking sedative activity.
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| BCC6088 | CK 666 |
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Inhibitor of the Arp2/3 complex; inhibits actin polymerization (IC<sub>50</sub> = 4 <span class='symbol'>μ</span>M).
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| BCC6089 | cis-Ned 19 |
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Irreversible nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist; inhibits Ca<sup>2+</sup> release (IC<sub>50</sub> = 800 nM) and [<sup>32</sup>P]NAADP binding (IC<sub>50</sub> = 15 <span class='symbol'>μ</span>M). Stereoisomer of <em>trans</em>-Ned 19. Fluorescently labels NAADP receptors in intact cells (excitation 351 and 365 nm using an ultraviolet Argon laser).
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| BCC6090 | Oxycodone hydrochloride |
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Potent and selective <span class='symbol'>μ</span>-opioid receptor agonist (K<sub>i</sub> values are 16 and >1000 nM for hMOR1 and hKOR1 respectively).
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