Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1633 - 1640 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6035 | SB 243213 dihydrochloride |
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Selective 5-HT2C inverse agonist (pKb = 9.8). Displays selectivity over other 5-HT2 subtypes (pKi values are 6.8, 7.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C respectively); also exhibits >100-fold selectivity over 50 other receptors, ion channels and enzymes. Displays anxiolytic activity in rat models.
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| BCC6036 | AT 56 |
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Orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) (K<sub>i</sub> = 75 <span class='symbol'>μ</span>M, IC<sub>50</sub> = 95 <span class='symbol'>μ</span>M). Inhibits the production of PGD<sub>2</sub> from PGH<sub>2</sub> <em>in vitro</em>, with no effect on PGE<sub>2</sub> or PGF<sub>2<span class='symbol'>α</span></sub> production.
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| BCC6037 | MMK 1 |
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Potent and selective human formyl peptide receptor FPR2 agonist (EC<sub>50</sub> values are 1, 2 and > 10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Induces migration of human monocytes and neutrophils via a chemotactic mechanism and enhances production of proinflammatory cytokines IL-1<span class='symbol'>β</span> and IL-6. Also activates the neutrophil superoxide-generating NADPH-oxidase.
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| BCC6038 | BAY-X 1005 |
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5-lipoxygenase activating protein (FLAP) inhibitor. Inhibits the synthesis of leukotrienes B<sub>4</sub> and C<sub>4</sub> in animal models; inhibits synthesis of leukotriene B<sub>4</sub> in A23187-stimulated leukocytes (IC<sub>50</sub> values are 0.026, 0.039 and 0.22 <span class='symbol'>μ</span>M for rat, mice and human leukocytes respectively). Displays anti-inflammatory activity. Orally active.
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| BCC6039 | CP 316819 |
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Selective glycogen phosphorylase inhibitor [IC<sub>50</sub> values are 0.017 and 0.034 <span class='symbol'>μ</span>M against human skeletal muscle glycogen phosphorylase a (huSMGPa) and liver glycogen phosphorylase a (huLGPa) respectively]. Antihyperglycemic agent.
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| BCC6040 | INH1 |
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Hec1 inhibitor. Binds Hec1, inhibiting its association with Nek2 and kinetochores. Causes arrest of mitosis and inhibits proliferation in breast cancer cell lines (GI<sub>50</sub>= 10 - 20 <span class='symbol'>μ</span>M).
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| BCC6041 | Parstatin (human) |
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Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR<sub>1</sub>) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC<sub>50</sub> ~ 3 <span class='symbol'>μ</span>M), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apoptotic activity <em>in vitro</em>. Inhibits angiogenesis and exhibits cardioprotective activity <em>in vivo</em>.
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| BCC6042 | Parstatin (mouse) |
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Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR<sub>1</sub>) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC<sub>50</sub> ~ 20 <span class='symbol'>μ</span>M), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apoptotic activity <em>in vitro</em>. Inhibits angiogenesis and exhibits cardioprotective activity <em>in vivo</em>.
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