Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8352 | Santalol |
| 1. Santalol has good antibacterial, anti-oxidation and anti-tumor activities. 2. α-Santalol is a potent antimitotic agent induced by interference with microtubule assembly. 3. α-Santalol shows a significant antifungal effect against a dermatophytic fungus, Trichophyton rubrum. | |
| BCC9242 | Neocurdione |
| 1. Neocurdione is an attachment inhibitor against the blue mussel, Mytilus edulis galloprovincialis. 2. Neocurdione shows a protective effect against D-GalN/tumor necrosis factor-alpha-induced liver injury in mice at a dose of 50 mg/kg p.o. | |
| BCC4952 | Tacrolimus (FK506) |
| 1. Tacrolimus versus ciclosporin are primary immunosuppression for kidney transplant recipients. | |
| BCC8339 | Mesaconine |
| 1. Mesaconine has cardiac effect. 2. Mesaconine has anti-NF-κB activity. 3. Mesaconine may be part of material basis of Mahuang Fuzi Xixin decoction on anti-inflammation and immune suppression. | |
| BCN8577 | Epitheaflagallin 3-O-gallate |
| 1. Epitheaflagallin 3-O-gallate shows antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinus glycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3. 2. Epitheaflagallin 3-O-gallate is a promising functional food material with potential antiobesity and antiperiodontal disease activities. 3. Epitheaflagallin 3-O-gallate suppresses tumor growth through the suppression of angiogenesis. | |
| BCN8432 | Octyl gallate |
| 1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Octyl Gallate shows antimicrobial activity against H. pylori, with a minimum inhibitory concentration (MIC) value of 125 ug/mL. 4. Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease. 5. Octyl Gallate is a potential anticancer agent, it exhibited decreased MCF-7 & MDA-MB-231 survival and induced apoptosis, with IC50 value of 40 uM. 6. Octyl gallate has antiviral activity, it shows an inhibitory effect on the growth of herpes simplex virus type 1 (HSV-1) in HEp-2 or Vero cells. 7. Octyl gallate shows antifungal activity against Saccharomyces cerevisiae ATCC7754 and Zygosaccharomyces bailii ATCC 60483. | |
| BCN3816 | Gardenin B |
| Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .Gardenin B-induced cell death in human leukemia cells involves multiple caspases but is independent of the generation of reactive oxygen species. Gardenin B can strongly inhibit biochemical production of nitric oxide (IC50=10.59±0.4 ug/mL). | |
| BCN8670 | Moscatin |
| 1. Moscatin exhibits antiplatelet aggregation activity. | |
