Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1985 - 1992 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6493 | Xanthone |
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Xanthone has antioxidant and anticorrosive properties, it performed excellently as a corrosion inhibitor for mild steel in sulphuric acid solution.
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| BCC6498 | GSK2801 |
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Selective BAZ2A and BAZ2B inhibitor (IC<sub>50</sub> values are 0.40 and 0.43 <span class='symbol'>μ</span>M, respectively). Selective for BAZ2A/B over TAF1L and BRD9. Cell permeable and orally available.
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| BCC6506 | BPTES |
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Allosteric glutaminase (GLS1) inhibitor (IC<sub>50</sub> = 3.3 <span class='symbol'>μ</span>M). Selective for GLS1 over GLS2 and <span class='symbol'>γ</span>-glutamyl transpeptidase. Induces cell death of P493 human lymphoma B cells <em>in vitro</em> and reduces tumor volume of P493 cell xenografts in mice.
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| BCC6508 | A-1210477 |
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Selective, high affinity Mcl-1 inhibitor (Ki = 454 pM). Disrupts Mcl-BIM complexes (IC50 in low μM range). Also inhibits Mcl-1NOXA interactions. Exhibits no effect on Bcl-XL-Bim or Bcl-X-BCL-Xs interactions. Induces apoptosis in multiple myeloma and non-small cell lung cancer cell lines and exhibits a synergistic effect with NavitoclaxTM to induce apoptosis in vitro. Cell permeable.
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| BCC6513 | SirReal2 |
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Selective SIRT2 inhibitor (IC<sub>50</sub> = 140 nM). Has minimal effect on SIRT1 and SIRT3-6. Increases <span class='symbol'>α</span>-tubulin acetylation levels in HeLa cells.
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| BCC6515 | Disodium (R)-2-Hydroxyglutarate |
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Oncometabolite produced by mutant isocitrate dehydrogenase 1 (IDH1) and IDH2. Inhibits KDM4A in murine embryonic fibroblasts resulting in activation of mTOR. Also activates NF-κB in bone marrow stromal cells.
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| BCC6521 | DEL-22379 |
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ERK dimerization inhibitor (IC<sub>50</sub> ~ 0.5 <span class='symbol'>μ</span>M); inhibits ERK dimerization without effecting phosphorylation or kinase activity. Suppresses growth of tumor cells expressing RAS-ERK oncogenes <em>in vitro</em>. Induces apoptosis and prevents tumor progression <em>in vivo</em>.
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| BCC6524 | P7C3 |
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NAMPT activator. Proneurogenic and neuroprotective. Protects newborn neurons in the dentate gyrus by mitigating cell death. Also enhances learning and memory in aged rats. Orally available and brain penetrant. Also revents doxorubicin-mediated toxicity in osteosarcoma cells and restores intracellular NAD levels.
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