Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCC4702 Pilocarpine HCl
1. Pilocarpine hydrochloride appears to be effective for dry mouth associated with Sjögren's syndrome. 2. Pilocarpine hydrochloride has acaricidal activity.
BCN8568 Saikogenin D
1. Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct inhibition of cyclooxygenase activity; and an elevation of [Ca2+]i that is attributed to Ca2+ release from intracellular stores. 2. Saikogenin D has immunomodulatory effect, it can attenuate IL-6 production in LPS-stimulated alveolar macrophages of B6 more than in that of BALB.
BCC8261 Uncarine C
1. Pteropodine acts as a positive modulator of muscarinic M(1) and 5-HT(2) receptors. 2. Pteropodine shows antigenotoxic, antioxidant and lymphocyte induction effects. 3. Pteropodine shows strong apoptotic effect on acute leukaemic lymphoblasts.
BCN3841 Inosine
Inosine, an endogenous purine nucleoside, has immunomodulatory, neuroprotective, and analgesic properties.Inosine is a cardiotonic agent, can treat cardiac disorders.Inosine can to be capable of forming base pairs with Adenine HFN72-P, Cytosine HDR44-O or Uracil BTP40-U thus contributing to genetic code degeneracy by causing stable mispairings.
BCN1627 Soyasaponin IV
1. Soyasaponin IV has hepatoprotective activity. 2. Soyasaponin IV has antimutagenic activity in mammalian cells.
BCN3842 Androsin
Androsin has antiasthmatic effects , it can prevent allergen- and platelet-activating factor (PAF)-induced bronchial obstruction (10 mg/kg orally; 0.5 mg inhalative).
BCN3843 Ecliptasaponin A
Ecliptasaponin A has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epithelial-mesenchymal transition.
BCN6523 Lysicamine
1. Lysicamine has antimicrobial and anti-inflammation activity, the minimum inhibitory concentrations of the pour component (Streptococcus mutans, Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Candida albicans.) is less than 5mg/ml for all four microorganisms and the minimum concentration with anti-inflammation is 0.2mg/ml for both IL-8 and IL-6. 2. Lysicamine has antileishmanial activity. 3. Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). 4. Lysicamine can significantly inhibit the proliferation of melanoma cells, it has antioxidative activity and chemopreventive activity in skin melanoma cells.