Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 1977 - 1984 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6478 | UF 010 |
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Class I HDAC inhibitor (IC<sub>50</sub> values are 0.06, 0.1, 0.5 and 1.5 <span class='symbol'>μ</span>M for HDACs 3, 2, 1 and 8, respectively). Exhibits >6-fold selectivity over other HDACs. Induces accumulation of acetylated histones in HCT116 cells <em>in vitro</em>. Inhibits proliferation of a range of cancer cell lines. Arrests cells at G<sub>1</sub>/S transition.
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| BCC6481 | Sanguinarine chloride |
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Sanguinarine chloride is a novel class of anti-Salmonella compounds, it could decrease the production of the SPI-1 type III secretion system main virulence proteins SipA and SipB and prevent the invasion of HeLa cells by Salmonella enterica serovar Typhimurium without affecting the growth of Salmonella. Sanguinarine chloride also shows cytotoxicity to cultured human cells from oral tissue.
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| BCC6482 | Triacetyl Resveratrol |
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Triacetylresveratrol has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NFκB, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells.
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| BCC6484 | PFI 4 |
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Potent and selective BRPF1 bromodomain inhibitor (IC50 = 80 nM). Exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. Disrupts BRPF1 binding to histone H3.3. Cell permeable.
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| BCC6489 | MN 64 |
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Potent and selective tankyrase (TNKS) inhibitor (IC<sub>50</sub> values are 6 and 72 nM for TNKS1 and TNKS2 respectively). Has no significant effect on PARP-1 or PARP-2 (IC<sub>50</sub> >19 <span class='symbol'>μ</span>M). Inhibits WNT/<span class='symbol'>β</span>-catenin signaling-dependent Super-TopFlash (STF) luciferase activity.
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| BCC6490 | Naproxen Sodium |
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Non-selective cyclooxygenase (COX) inhibitor that displays anti-inflammatory, antipyretic and analgesic effects. Has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.
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| BCC6491 | 3-Indolebutyric acid (IBA) |
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Indole-3-butyric acid (3-indolebutyric acid; IBA) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate.
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| BCC6492 | Sclareolide |
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Sclareolide demonstrates a good antibacterial activity against Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27950, Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212. Sclareolide enhances gemcitabine‑induced cell death through mediating the NICD and Gli1 pathways in gemcitabine‑resistant human pancreatic cancer.
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