Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8531 | 3-Epibetulinic acid |
| 1. Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin. | |
| BCN3840 | Diallyl disulfide |
| Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22. Diallyl disulfide induces antioxidant defense mechanism by activating Nrf2 pathway and reduces inflammatory response by inhibiting NF-κB activation. Diallyl disulfide also has protective effect against CP-induced developmental toxicity. | |
| BCN8512 | Emodin-1-O-glucoside |
| 1. Emodin 1-O-beta-D-glucoside has neuroprotective and uncoupling activities, and that it may be the a new uncoupler of nNOS-PSD-95. 2. Emodin 1-O-beta-D-glucoside shows inhibitory effects on various tumor cells proliferation. | |
| BCN8672 | Resveratroloside |
| 1. Resveratroloside has anti-inflammatory activity, it shows similar nitric oxide (NO) inhibition potency as that of piceid (the major constituent of P. cuspidatum). 2. Resveratroloside has cardioprotective effect. 3. Resveratroloside can inhibit hydroxylation of testosterone by CYP3A4. 4. Resveratroloside exhibits α-glucosidase inhibitory activity. | |
| BCN8565 | Periplocoside N |
| 1. Periplocoside N possesses insecticidal activities against the red imported fire ant. | |
| BCN8374 | Nervonic acid |
| 1. Nervonic acid can inhibit DNA polymerase beta and HIV-1 reverse transcriptase. 2. Nervonic Acid improves learning memory ability in normal mice and mice with experimental memory impairment. | |
| BCN8390 | Myristic acid |
| 1. Myristic acid supports the immediate inhibitory effect of lauric acid on ruminal methanogens and methane release. 2. Dietary myristic acid modifies the HDL-cholesterol concentration and liver scavenger receptor BI expression in the hamster. 3. Myristic acid increases the activity of dihydroceramide Δ4-desaturase 1 through its N-terminal myristoylation. | |
| BCN8291 | Dodecanoic acid ingenol ester |
| 1. 13-Oxyingenol dodecanoat shows moderate cytotoxicity with IC50 values being 35.59 ± 5.37 μmol·L-1 (Caco-2), 24.04 ± 4.70 μmol·L-1 (MCF-7), and 22.24 ± 5.19 μmol·L-1 (MCF-7/ADM). | |
