Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC9143 | Senkyunolide G |
| 1. Senkyunolide G and senkyunolide I could serve as pharmacokinetic markers for sepsis care. | |
| BCN8549 | Cistanoside F |
| 1. Cistanoside F shows vasorelaxant activity. 2. Cistanoside F has antioxidative effect, it shows a strong free radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthine oxidase (XOD) generated superoxide anion radical (O2-.). | |
| BCN1634 | Tamoxifen |
| 1. Tamoxifen acts as an estrogen agonist by preventing the skeletal alterations that result from ovarian hormone deficiency. 2. Tamoxifen is currently the first-line therapy for treatment of hormone-dependent breast cancer. | |
| BCN3861 | Polygalacin D |
| 1. Polygalacin D can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxic effect on RAW 264.7 macrophages, and can suppress induction by LPS of pro-inflammatory cytokines such as prostaglandin E2 (PGE2). 2. Polygalacin D2 exhibits significant inhibition on the proliferation of five kinds of cultured human tumor cell lines, i. e., A549 (non-small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nerve system) and HCT-15 (colon), in vitro. 3. Polygalacin D shows hepatoprotective activities against HSC-T6 cell line in vitro. | |
| BCN3862 | Escin IA |
| Escin IA is a prodrug and its structure can be converted to desacylescin I by human intestinal bacteria and Lactobacillus brevis., desacylescin I as a biotransformation product shows potentially inhibitory effects on mouse tumor, and a potential candidate for anti tumor agents. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of EMT process by down-regulating LOXL2 expression. | |
| BCN3863 | Gypenoside XLVI |
| 1. Gypenoside XLVI shows strong cytotoxic activity against A549 cells, with the IC50 values of 52.63±8.31 ug/ml. | |
| BCN3865 | Purpureaside C |
| 1. Purpureaside C has significant proinflammatory, antimicrobial and immunomodulating effects. | |
| BCN3866 | 6''-O-Acetylglycitin |
| 1. 6''-O-Acetylglycitin is a potential nutriceutical. | |
