Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6546 | Vulpic acid |
| 1. Vulpic acid can inhibit one or more enzymes (PfFabI, PfFabG, and PfFabZ) from the plasmodial fatty acid biosynthesis (FAS-II) pathway, a potential drug target for liver stage activity. 2. Vulpic acid has therapeutic and prophylactic potential to be antibacterial and antiplasmodial agents. | |
| BCN6538 | 7,8-Benzoflavone |
| 7,8-Benzoflavone is one of the most potent inhibitors of breast cancer resistance protein (BCRP). | |
| BCN6545 | Quercetin-3-O-glucose-6'-acetate |
| 1. Quercetin-3-O-glucose-6''-acetate has antioxidant capacity. 2. Quercetin-3-O-glucose-6''-acetate is a NADPH oxidase inhibitor. | |
| BCN6543 | Kojic acid |
| 1. Kojic acid exhibits a competitive inhibition for the oxidation of chlorogenic acid and catechol by potato polyphenol oxidase (PPO) and of 4-methylcatechol and chlorogenic acid by apple PPO. 2. Kojic acid has significant tyrosinase inhibitory activity. 3. Kojic acid has been used as a food additive for preventing enzymatic browning of crustaceans and as a cosmetic agent for skin whitening. 4. Kojic acid exhibits concentration-dependent scavenging activity on DPPH possessing strong antioxidant activity, it can reduce the mortality induced by gamma irradiation. | |
| BCC5210 | Procaine |
| Procaine is a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. It is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells, it inhibits the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells. | |
| BCN6539 | 7-Hydroxyflavanone |
| 1. 7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates, it could be useful for the development of a novel respiratory infections treatment. | |
| BCN6553 | Hederacolchiside A1 |
| 1. Hederacolchiside A1 shows antiproliferation activities in three cancer cell lines with the IC50 value of 2.4 uM. 2. Hederacolchiside A1 has antimelanoma potential. 3. Hederacolchiside A1 exhibits a preferential cytotoxicity on a pigmented melanoma cell line. 4. Hederacolchiside A1 shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. | |
| BCC2968 | H-Leu-OH |
| L-Leucine is an essential amino acid for the human body, L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway, and an excess of dietary l-leucine has been shown to retard the growth of rats fed low-protein diets or diets deficient in isoleucine. | |
