Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2113 - 2120 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6664 | 1,3-Dipropyl-8-phenylxanthine |
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Selective A1 adenosine antagonist.
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| BCC6665 | (±)-U-50488 hydrochloride |
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Selective <span class='symbol'>κ</span>-opioid agonist. At higher concentrations blocks Na<sup>+</sup> channels. Separate isomers (+)-U-50488</a> and (-)-U-50488</a> also available .
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| BCC6666 | (-)-U-50488 hydrochloride |
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More active enantiomer of (±)-U-50488. (+)-U-50488 hydrochloride also available.
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| BCC6667 | AG 99 |
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Epidermal growth factor receptor (EGFR) kinase inhibitor (IC<sub>50</sub> = 10 <span class='symbol'>μ</span>M) that is selective over insulin receptor kinase. Blocks tyrosine phosphorylation of p145<sup>met</sup> and promotes cell death of normal and cancer cells via activation of caspase-like proteases <em>in vitro</em>.
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| BCC6668 | U-54494A hydrochloride |
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<span class='symbol'>κ</span>-opioid agonist and anticonvulsant. Perhaps acts as an NMDA antagonist.
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| BCC6669 | N1,N12-Diethylspermine tetrahydrochloride |
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Powerful antineoplastic agent in cultured cells and animal tumors (IC<sub>50</sub> = 0.2 <span class='symbol'>μ</span>M in L1210 cells). Inhibitor of polyamine synthases. Suppressor of mitochondrial DNA synthesis.
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| BCC6670 | Diphenyleneiodonium chloride |
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GPR3 agonist (EC<sub>50</sub> = 1 <span class='symbol'>μ</span>M); activates adenylate cyclase through GPR3 but not GPR6 or GPR12. Also induces Ca<sup>2+</sup> mobilization and <span class='symbol'>β</span>-arrestin receptor internalization. Binds strongly to flavoproteins; inhibits several enzymes, including NO synthase, NADPH oxidases and NADPH cytochrome P450 oxidoreductase. Also inhibits platelet aggregation.
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| BCC6671 | Dihydroergotoxine mesylate |
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A complex of closely related alkaloid salts. Binds with high affinity to the GABA<sub>A</sub> receptor Cl<sup>-</sup> channel, producing an allosteric interaction with the benzodiazepine site. Also interacts with central dopaminergic, serotonergic and adrenergic (<span class='symbol'>α</span><sub>1</sub>) receptors. Displays antiproliferative activity <em>in vitro</em> (IC<sub>50</sub> = 18 - 38 <span class='symbol'>μ</span>M in prostate cancer cells) and exhibits cognition-enhancing, anticonvulsant and sedative activity <em>in vivo</em>. Orally active.
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