Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3933 | Paeoniflorigenone |
| 1. Paeoniflorigenone is a depolarizing neuromuscular blocking agent, being similar to succinylcholine. 2. Paeoniflorigenone is cytotoxic and induces apoptosis selectively in the cancer cell lines. 3. Paeoniflorigenone may take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation. 4. Paeoniflorigenone shows anti-inflammatory effects. | |
| BCN3934 | Hesperetin 5-O-glucoside |
| 1. Hesperetin 5-O-glucoside has hypocholesterolemic effect. | |
| BCN3935 | Cristacarpin |
| 1. Cristacarpin exhibits moderate but selective activity towards DNA repair-deficient yeast mutants. 2. Cristacarpin promotes endoplasmic reticulum (ER) stress, leading to sub-lethal reactive oxygen species (ROS) generation and which eventually terminates by triggering senescence in pancreatic and breast cancer cells through blocking the cell cycle in the G1 phase. | |
| BCN3936 | Obtucarbamate A |
| 1. Obtucarbamate A has antitussive activity. 2. Obtucarbamate A exhibits significant inhibitory effect against neuroinflammation with the IC50 value of 10.57 uM . | |
| BCN3937 | Obtucarbamate B |
| 1. Obtucarbamate B has antitussive activity. | |
| BCN3938 | Falcarinol |
| 1. Falcarinol has effects on CaCo-2 cells appear to be biphasic, inducing pro-proliferative and apoptotic characteristics at low and high concentrations of Falcarinol, respectively. 2. Falcarinol-associated dermatitis is due to antagonism of the CB(1) receptor in keratinocytes, leading to increased chemokine expression and aggravation of histamine action. | |
| BCN1359 | 6alpha-Hydroxycleroda-3,13-dien-16,15-olid-18-oic acid |
| 1. (-)-6β-Hydroxy-5β,8β,9β,10α-cleroda-3,13-dien-16,15-olid-18-oic acid is one alpha- glucosidase inhibitory constituent from Duranta repens. | |
| BCN3942 | Cuspidiol |
| 1. Cuspidiol shows cytotoxicity against Jurkat T cell clone E6.1 at 7.3 ug/mL. | |
