Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3945 | Dodoviscin J |
| 1. Dodoviscin J can promote adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells. | |
| BCN1573 | 1,2-Methylenedioxy-3,10,11-trimethoxynoraporphine |
| 1. 1,2-Methylenedioxy-3,10,11-trimethoxyaporphine exerts moderate vessel-relaxing activities with the IC 50 value from 16.50 to 32.81 microM at the test concentrations. | |
| BCN3949 | Coumestrol |
| 1. Coumestrol suppresses the accumulation of HIF-1α via suppression of SPHK1 pathway in hypoxic PC-3 cells. 2. Coumestrol is a novel inducer of mitochondrial biogenesis through the activation of Sirt1. 3. Coumestrol can function by inhibiting oncogenic disease, at least in part, through CKII inhibition-mediated cellular senescence. 4. Coumestrol treatment is effective in preventing neuronal loss in all times of administration as well as able to rescue the Na+, K+ -ATPase activity, suggesting its potential benefits for either prevention or therapeutics use against cerebral ischemia in males. | |
| BCN3950 | Cepharadione A |
| 1. Cepharadione A, a naturally occurring DNA damaging agent. | |
| BCN3953 | Ginsenoyne K |
| 1. Ginsenoyne K shows dose-dependent inhibitory effect on dopa oxidase activity of tyrosinase. | |
| BCN3954 | Pedalitin |
| 1. Pedalitin is a mixed-type inhibitor of tyrosinase. 2. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl rosmarinate and Pedalitin are mixed-type inhibitors. | |
| BCN3957 | Goniopypyrone |
| 1. (+)-Goniopypyrone suppresses the growth of cultured Ehrlich ascites tumor cells as well as PU5-1.8 cells. | |
| BCN3958 | Goniodiol |
| 1. (+)-Goniodiol and 7-epi-(+)-Goniodiol show high antibacterial activity (MIC, 3.1 mM) against Yersinia intermedia. | |
