Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN4028 | Cyclo(D-Leu-L-Pro) |
| 1. Cyclo(D-Leu-L-Pro) shows antitumour and antifungal activities. | |
| BCN4029 | Cyclo(L-Phe-L-Pro) |
| 1. Cyclo(L-Phe-L-Pro) shows antifungal and broad spectrum antibacterial activities. 2. Cyclo-(L-Phe-L-Pro) exhibits activity against methicillin-resistant S. aureus ATCC 43300 and Enterococcus raffinosus, with low toxicity against human hepatoma HepaRG cells. | |
| BCN4032 | Mulberrofuran C |
| 1. Mulberrofuran C shows protective effects on t-BHP-induced oxidative stress with the EC50 value of 0.41 ± 0.48 uM ; it also shows protective effects on glutamate-induced cell death with the EC50 value of 16.50 ± 7.82 uM. 2. Mulberrofuran C has antiviral effects against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2). | |
| BCN4037 | Piplartine |
| 1. Piplartine shows potential anti-malaria and anti- leishmaniasis activities. 2. Piplartine shows inhibitory activities of platelet aggregation induced by ADP and AA in vitro . 3. Piplartine displays in vitro and in vivo anticancer efficacy. 4. Piplartine induces in vivo and in vitro mutagenicity in eukaryotic models. | |
| BCN4039 | Aristolone |
| Aristolone is a natural product from the leaf oil of Alpinia polyantha. | |
| BCN4040 | Nagilactone C |
| 1. Nagilactone C possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 microg/ml, respectively. 2. Nagilactone C and phyllanthoside are novel protein synthesis inhibitors, they are specific for the eukaryotic translation apparatus, function in vivo and in vitro, and interfere with translation elongation. 3. Nagilactone C shows high insecticidal activity against second-instar nymphs of Eocanthecona furcellata. | |
| BCN4042 | Pyrroside B |
| 1. Pyrroside B shows stronger antioxidative activity than that of α-tocopherol. | |
| BCN4043 | Pellitorine |
| 1. Pellitorine shows strong cytotoxic activities against HL60 and MCT-7 cell lines. 2. Pellitorine can suppress expression of inducible NO synthase and cyclooxygenase-2. 3. Pellitorine shows antiprotozoal activity against Plasmodium falciparum (IC50 = 3.3 ug/mL). 4. Pellitorine is a potential larvicide with a specific target site and a lead molecule for the control of mosquito populations. 5. Pellitorine shows potent antiplatelet aggregation activity. | |
