Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN4004 | Moracin O |
| 1. Moracin O and moracin P exhibit potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia. 2. Moracin O shows significant neuroprotective activity against glutamate-induced cell death in SK-N-SH cells. 3. Moracin O demonstrates a remarkable inhibition of the acetic acid-induced pain. 4. Moracin O has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 uM. | |
| BCN4007 | (Z)-Butylidenephthalide |
| 1. (Z)-Butylidenephthalide has antitumor effect, can effectively inhibit the tumor growth in the glioma. | |
| BCN4012 | Cyclo(L-Ala-L-Pro) |
| Cyclo(L-Ala-L-Pro) and cyclo(L-Val-L-Pro) inhibit aflatoxin production of Aspergillus parasiticus and Aspergillus flavus in liquid medium at concentrations of several hundred uM without affecting fungal growth. | |
| BCN4014 | Methyl 4-hydroxycinnamate |
| Methyl 4-hydroxycinnamate is a model chromophore of the Photoactive Yellow Protein (PYP). Methyl 4-hydroxycinnamate can reduce IL-8 secretion at 10 ug/mL treatment concentrations; it may significantly contribute to antibacterial activities of Noni leaves. | |
| BCN4016 | Tubotaiwine |
| 1. Tubotaiwine shows selective activity against L. infantum. 2. Tubotaiwine and apparicine have affinity for adenosine receptors in the micromolar range and also have in-vivo analgesic activity in mice. | |
| BCN4020 | 6,7-Dihydroneridienone A |
| 1. 6,7-Dihydroneridienone A exhibits notable leishmanicidal activity. | |
| BCN4023 | Methyl ferulate |
| 1. Methyl ferulate is a possible inhibitor of the mitogen activated phosphor kinase pathway. 2. Methyl ferulate could be a potential anti-inflammatory agent isolated for the first time in medicinal plant S. tuberosa. 3. Methyl ferulate has promising anthelmintic activity against Haemonchus contortus. | |
| BCN4026 | Tsugafolin |
| 1. Tsugafolin has weak anti-HIV activity. | |
