Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6508 | Demethylsuberosin |
| 1. Demethylsuberosin displays suppressive effects on LPS-induced NO and PGE2 production with the IC50 value of 9.42 uM, suggests that it has potential anti-inflammatory activity. | |
| BCN6509 | Akuammidine |
| 1. Akuammidine shows anti-inflammatory and anti-asthmatic properties. 2. Akuammidine has opioid analgesic activity, it shows a preference for mu-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 microM at mu-, delta- and kappa-opioid binding sites, respectively. | |
| BCN6417 | Fargesone A |
| 1. Fargesone A shows inhibitory effects on nitric oxide (NO) production in the lipopolysaccharide plus interferon-gamma activated-murine macrophage cell line, J774.1. | |
| BCN6512 | 2',4'-Di-O-(E-p-coumaroyl)afzelin |
| Antimicrobial agent. | |
| BCN6514 | Hannokinol |
| (+)-Hannokinol and MESO-hannokinol can significantly inhibit lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 microM to 100 microM. | |
| BCN6416 | Futoquinol |
| 1. Futoquinol can potently inhibit NO production with an IC(50) value of 16.8microM in microglia cells, suggests that it has anti-neuroinflammatory activities. 2. Futoquinol shows potent inhibition of PMA-induced ROS production in human polymorphonuclear neutrophils with IC(50) values 13.1 +/- 5.3 microM. 3. Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), the Chinese drug haifengteng. | |
| BCN6515 | Kadsurin A |
| 1. Kadsurin A and Kadsurin B have anti-platelet activating factor activities. | |
| BCN6517 | Protosappanin A dimethyl acetal |
| 1. Protosappanin A dimethyl acetal shows significant xanthine oxidase inhibitory activity in a concentration-dependent manner. | |
