Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2241 - 2248 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6796 | (±)-Anatoxin A fumarate |
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A potent nicotinic agonist (K<sub>i</sub> values are 1.25 and 1840 nM for <span class='symbol'>α</span>4<span class='symbol'>β</span>2 and <span class='symbol'>α</span>7 nicotinic receptors respectively). Stimulates [<sup>3</sup>H]-dopamine release from rat striatal synaptosomes (EC<sub>50</sub> = 136 nM).
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| BCC6797 | Efaroxan hydrochloride |
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Potent, highly selective <span class='symbol'>α</span><sub>2</sub> adrenoceptor antagonist and imidazoline I<sub>1</sub> receptor ligand (pK<sub>i</sub> values are 7.87, 7.42, 5.74, 7.28 and < 5 for <span class='symbol'>α</span><sub> 2A</sub>, <span class='symbol'>α</span><sub>2B</sub>, <span class='symbol'>α</span><sub>2C</sub>, I<sub>1</sub>, and I<sub>2</sub> receptors respectively). Promotes insulin secretion, at a site distinct from I<sub>1</sub> or I<sub>2</sub> (the putative I<sub>3</sub> receptor) <em>in vitro</em> and <em>in vivo</em>.
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| BCC6798 | Idazoxan hydrochloride |
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<span class='symbol'>α</span><sub>2</sub>-adrenoceptor antagonist, and I<sub>2</sub> ligand, selective over I<sub>1</sub> sites (pK<sub>i</sub> values are 5.90, 7.22, 8.01, 7.43, and 7.7 for I<sub>1</sub>, I<sub>2</sub>, <span class='symbol'>α</span><sub>2A</sub>, <span class='symbol'>α</span><sub>2B</sub>, and <span class='symbol'>α</span><sub>2C</sub> receptors respectively).
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| BCC6799 | DIPPA hydrochloride |
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An irreversible and selective antagonist at the <span class='symbol'>κ</span> receptor, with persistent effect <em>in vivo</em>.
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| BCC6800 | 8-Hydroxy-PIPAT oxalate |
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High affinity 5-HT<sub>1A</sub> receptor agonist (K<sub>d</sub> = 0.38 nM). 7-Hydroxy-PIPAT maleate also available.
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| BCC6801 | MSOP |
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Selective group III metabotropic glutamate receptor antagonist. Displays an apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord compared to > 700 μM for the (1S,3S)-ACPD-sensitive presynaptic mGlu in the same system. Has no activity on postsynaptic mGlu receptors or on ionotropic glutamate receptors on neonatal rat motoneurons. Also available as part of the Group III mGlu Receptor Tocriset™.
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| BCC6802 | (S)-3,5-DHPG |
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Selective group I mGlu receptor agonist. Also available as part of the Group I mGlu Receptor and Mixed mGlu Receptor. (<em>RS</em>)-3,5-DHPG also available.
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| BCC6803 | THIP hydrochloride |
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Systemically active GABA<sub>A</sub> receptor agonist and GABA<sub>A</sub>-<span class='symbol'>ρ</span> receptor antagonist. Displays antinociceptive, anticonvulsant and sedative effects. Hypnotic agent that enhances delta activity within non-REM sleep in rats.
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