Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN3959 | 3-O-Caffeoyloleanolic acid |
| 1. 3-O-Caffeoyl oleanolic acid exhibits in vitro cytotoxicity against the A549 cell line with the CC50 values of less than 20 ug/mL. | |
| BCN3960 | Caulilexin C |
| 1. Caulilexin C shows inhibitory activity on human Acyl CoA: cholesterol transferase I (hACATI) and on human Acyl CoA: cholesterol transferase 2 (hACAT2) at 100 mug/ml. | |
| BCN3961 | 8-Lavandulylkaempferol |
| 1. 8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, respectively. 2. 8-Lavandulylkaempferol shows inhibitory activities against aldose reductase, with the the IC50 of 0.79 microM. | |
| BCN3962 | Phaseollidin hydrate |
| 1. Phaseollidin hydrate shows less antifungal activity than the original phytoalexin phaseollidin. | |
| BCN3964 | Paeonilactone C |
| 1. Paeonilactone C significantly protects primary cultures of rat cortical cells against H2O2-induced neurotoxicity. | |
| BCN3965 | Angophorol |
| 1. Angophorol exerts potential anticancer activity through growth inhibition and apoptosis in K562 cells. | |
| BCN3969 | Syzalterin |
| 1. Syzalterin can protect PC12 cells effectively against Abeta-induced toxicity. | |
| BCN3972 | Guajadial B |
| 1. Guajadial B shows cytotoxicities against five human cancer cell lines, it is the most effective having an IC50 value of 150 nM toward A549 cells. 2. Guajadial B acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage. | |
