Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN4061 | Barbinervic acid |
| 1. Barbinervic acid shows anti-bacteria activity (IC50 = 0.098 g x LU(-1), IC50 = 0.27 g x L(-1)) against SA and ESBLs-SA respectively. | |
| BCN1320 | 2,3-Dihydroamentoflavone 7,4'-dimethyl ether |
| 1. 2,3-Dihydroamentoflavone 7,4'-dimethyl ether exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 and/or HT-29 cell lines in vitro. | |
| BCN4063 | 9-O-Methyl-4-hydroxyboeravinone B |
| 1. 9-O-Methyl-4-hydroxyboeravinone B is a promising candidate for cancer therapy. | |
| BCN4065 | 4beta-Carboxy-19-nortotarol |
| 1. 4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced by Fe(III)-ADP/ NADH, it inhibits linoleic acid autoxidation but not generation of superoxide anion. | |
| BCN4071 | Mirabijalone D |
| 1. Mirabijalone D is a non-competitive inhibitor based on the Dixon plot. 2. Mirabijalone D inhibits Aβ1–42 production by 43.7% in APPSW-N2a cells. | |
| BCN4074 | Methyleugenol |
| Methyleugenol (ME) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its presence in food products with effective analytical methods. ME has elaxant and antispasmodic actions on guinea-pig isolated ileum, it also has antinociceptive, anti-inflammatory, and insecticidal properties.ME can inhibit the production of nitric oxide and decreased the protein expression of inducible nitric oxide synthase, it down-regulates the production of pro-inflammatory cytokines in the ischemic brain as well as in immunostimulated mixed glial cells. | |
| BCN4081 | Cycloolivil |
| 1. (+)-Cycloolivil and oleuropein are natural polyphenolic compounds with a significant radical scavenging activity present in olive tree, they can reduce the ability of thrombin to stimulate platelet aggregation, this effect is greater in platelets from patients with type 2 diabetes mellitus than in controls;suggest that they may prevent thrombotic complications associated to platelet hyperaggregability and be the base for the development of antiaggregant therapeutic strategies. 2. (+)-Cycloolivil is an antioxidant. | |
| BCN4082 | 3'-Methoxydaidzein |
| 1. 3'-Methoxydaidzein and geraldol have antiplatelet aggregation activity and appear to be specific against collagen‐induce platelet aggregation with a IC50 values of12.3 and 61.5 uM, respectively. 2. 3'-Methoxydaidzein has antioxidant activity. | |
