Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8661 | Glicoricone |
| 1. Glicoricone acts as a partial estrogen antagonist. 2. Glicoricone inhibited the enzyme with the IC50 (concentration required for 50% inhibition of the enzyme activity) values of 6.0 x 10(-5)-1.4 x 10(-4) M. | |
| BCC8152 | Clemastanin B |
| 1. Clemastanin B exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. 2. Clemastanin B has antioxidant and anti-inflammatory activities. | |
| BCN8587 | Glyasperin C |
| 1. Glyasperin C acts as a partial estrogen antagonist. 2. Glyasperin C shows potent anti-vancomycin-resistant Enterococci effects (MIC 1.9 × 10-5-4.5 × 10-5 M for E. faecium and E. faecalis). 3. Glyasperin C shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candidate in the design of skin-whitening agents. | |
| BCN8280 | Lappaol A |
| 1. Lappaol A has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. 2. Lappaol A has potential chemosensitizing activity, it may be candidates for developing novel adjuvant anticancer agents. | |
| BCN8676 | Lappaol C |
| 1. Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. 2. Lappaol C has potential chemosensitizing activity, it may be candidates for developing novel adjuvant anticancer agents. | |
| BCN8665 | Lappaol F |
| 1. Lappaol F has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. 2. Lappaol F has potential chemosensitizing activity, it may be candidates for developing novel adjuvant anticancer agents. 3. Lappaol F exhibits antitumor activity in vitro and in vivo and has strong potential to be developed as an anticancer therapeutic. 4. Lappaol F strongly inhibited NO production in the LPS-stimulated RAW264.7 cells with the IC(50) value of 9.5 microM. | |
| BCN1626 | 7,2',4'-Trihydroxy-5-methoxy-3-phenylcoumarin |
| 1. 7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells. | |
| BCN8615 | Suspenoidside B |
| 1. Suspenoidside B possesses strong hepatoprotective activities against the damage in HepG2 cell. | |
