Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2289 - 2296 of 9359 hot products
| Catalog No. | Product Name |
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| BCC6844 | Remoxipride hydrochloride |
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Dopamine D2 receptor antagonist showing selectivity over D3 and D4 receptors (Ki values are ~ 300, ~ 1600, and ~ 2800 nM for D2, D3 and D4 receptors respectively). Exhibits antipsychotic activity in vivo with no extrapyramidal side effects. 50-fold more potent than sulpiride in antagonising the effects of apomorphine in the rat.
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| BCC6845 | 3-CPMT |
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This cocaine analog binds with high affinity to the dopamine transporter (K<sub>i</sub> = 30 nM) and blocks re-uptake of dopamine. However, it is a weak psychomotor stimulant and does not substitute for cocaine in addicted rats.
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| BCC6846 | 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride |
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Potent inhibitor of dopamine uptake and transport (K<sub>i</sub> = 11.8 nM).
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| BCC6847 | TRIM |
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A potent inhibitor of neuronal and inducible NO synthases, with much lower affinity for the endothelial isoform (displays IC<sub>50</sub> values of 28.2, 27.0 and 1057.5 <span class='symbol'>μ</span>M respectively). Antinociceptive <em>in vivo</em>.
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| BCC6848 | SKF 38393 hydrobromide |
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Prototypical D1-like dopamine receptor selective partial agonist (Ki values are 1, ~ 0.5, ~ 150, ~ 5000 and ~ 1000 nM for D1, D5, D2, D3 and D4 receptors respectively).
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| BCC6849 | SCH 23390 hydrochloride |
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Potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively). Also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3 nM and 9.3 nM respectively). Blocks quinpirole-induced Kir3 (GIRK) currents (EC50 = 268 nM) independently of receptors.
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| BCC6850 | β-Funaltrexamine hydrochloride |
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Selective <span class='symbol'>μ</span> opioid receptor antagonist.
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| BCC6851 | ARC 239 dihydrochloride |
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Selective <span class='symbol'>α</span><sub>2B</sub> adrenoceptor antagonist (pK<sub>D</sub> values are 8.8, 6.7 and 6.4 at <span class='symbol'>α</span><sub>2B</sub>, <span class='symbol'>α</span><sub>2A</sub>, and <span class='symbol'>α</span><sub>2D</sub> receptors respectively). Also available as part of the <span class='symbol'>α</span><sub>2</sub>-Adrenoceptor.
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