Hot Natural Products & Bioactive Compounds

BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.

Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.

Hot Products from BioCrick

Showing 2337 - 2344 of 9359 hot products

BioCrick hot natural products and bioactive compounds
Catalog No. Product Name
BCC6892 LY 235959
Competitive NMDA receptor antagonist.
BCC6893 CGP 20712 dihydrochloride
Highly selective and potent <span class='symbol'>&beta;</span><sub>1</sub>-adrenoceptor antagonist (IC<sub>50</sub> = 0.7 nM). Displays 10,000-fold selectivity over <span class='symbol'>&beta;</span><sub>2</sub>-adrenoceptors. Also available as part of the <span class='symbol'>&#946;</span>-Adrenoceptor Antagonist.
BCC6894 Nisoxetine hydrochloride
A potent and selective inhibitor of noradrenalin uptake with little or no affinity for a range of other neurotransmitter receptors.
BCC6895 PHCCC
Group I metabotropic glutamate receptor antagonist (IC<sub>50</sub> ~ 3 <span class='symbol'>&mu;</span>M); 67 times more potent than (S)-4-carboxyphenylglycine. Also a positive allosteric modulator for mGlu<sub>4a</sub>; potentiates L-AP4-mediated inhibition of striatopallidal synaptic transmission <em>in vitro</em>. Displays antiParkinsonian effects in rats <em>in vivo</em>.
BCC6896 CPCCOEt
hmGlu<sub>1</sub> subtype-selective non-competitive antagonist (IC<sub>50</sub> = 6.5 <span class='symbol'>&mu;</span>M). Has no agonist or antagonist activity at hmGlu<sub>2, 4a, 5a, 7b, 8a</sub> or ionotropic receptors at concentrations of up to 100 <span class='symbol'>&mu;</span>M.
BCC6897 Methyllycaconitine citrate
Potent antagonist for <span class='symbol'>&alpha;</span>7-containing neuronal nicotinic receptors (K<sub>i</sub> = 1.4 nM). Interacts with <span class='symbol'>&alpha;</span>4<span class='symbol'>&beta;</span>2 and <span class='symbol'>&alpha;</span>6<span class='symbol'>&beta;</span>2 receptors at concentrations &gt; 40 nM. Attenuates METH-induced neurotoxicity in mouse striatum <em>in vivo</em>.
BCC6898 Piribedil dihydrochloride
A direct dopamine agonist, in clinical use for treatment of dopaminergic system dysfunction. Recent work suggests that it is selective for the D3 subtype, for which it has 20 times higher affinity than for D2, and possesses no significant affinity for D1 receptors.
BCC6899 CP 93129 dihydrochloride
Potent and highly selective 5-HT1B agonist (Ki values are 8.1, 1100, 1500, 2900 and 7200 nM for 5-HT1B, 5-HT1D, 5-HT1A, 5-HT1c and 5-HT2, respectively). Reduces food intake and decreases body weight in rats.