Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6827 | Sikokianin C |
| 1. Sikokianin C shows antimalarial activity against the chloroquine-resistant strain of Plasmodium falciparum, with the IC (50) value of 0.56 microg/mL. | |
| BCN6828 | Licoflavonol |
| 1. Licoflavonol exhibits a strong inhibitory effect on the secretion of the SPI-1 effector proteins via regulating the transcription of the SicA/InvF genes, and the transportation of the effector protein SipC, thus, it is a novel natural inhibitor of Salmonella T3SS, could be a promising candidate for novel type of anti-virulence drugs. | |
| BCN6829 | Dehydroglyasperin D |
| 1. Dehydroglyasperin D exhibits anti-obesity, antioxidant and anti-aldose reductase effects. 2. Dehydroglyasperin D has potent anticancer activity, it inhibits the proliferation of HT-29 human colorectal cancer cells through direct interaction with phosphatidylinositol 3-kinase. 3. Dehydroglyasperin D may be a promising anti-inflammatory agent that mediates suppression of both COX-2 expression and the MLK3 signalling pathway through direct binding and inhibition of MLK3. 4. Dehydroglyasperin D shows strong ferric reducing activities and effectively scavenged DPPH, ABTS(+), and singlet oxygen radicals. | |
| BCN6832 | 3,9-Dihydroeucomin |
| 1. (+/-)-3,9-Dihydroeucomin has immunomodulatory effects, it shows inhibitory effects on PBMC proliferation activated by PHA with the IC(50) value of 19.4 microM. | |
| BCN6833 | Topazolin |
| 1. Topazolin has weak fungitoxic activity. 2. Topazolin displays significant activity against Salmonella typhimurium ATCC 13311 with MIC values ranging from 2 to 8 ug/mL, it also shows in vitro free radical scavenging activities with IC50 values in the range of 0.18-0.56 mg/mL. | |
| BCN6834 | Maackiaflavanone |
| 1. Maackiaflavanone B shows cytotoxic activity with IC(50) value of 7.8 microM against human cancer cell line A375S2. | |
| BCN6835 | Isolupalbigenin |
| 1. Isolupalbigenin shows promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 uM). 2. Isolupalbigenin shows in vitro inhibitory activity toward human glyoxalase I. 3. Isolupalbigenin shows two different antibacterial activities against MRSA: direct growth inhibition and intensification of methicillin sensitivity, it could lead to the development of compounds for new approaches against MRSA infection. | |
| BCN6836 | Glyasperin D |
| 1. Glyasperin D possesses weak anti-Helicobacter pylori activity. | |
