Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6954 | Taurocholic acid |
| 1. Rectal administration of taurocholic acid can stimulate glucagon-like peptide-1 and peptide YY by TGR5 receptor activation, which may have potential for the management of type 2 diabetes and obesity. 2. Taurocholic acid feeding prevents tumor necrosis factor-alpha-induced damage of cholangiocytes by a PI3K-mediated pathway. 3. Taurocholic acid feeding shows cytoprotective effects on the biliary tree after adrenergic denervation of the liver. 4. High concentraction of taurocholic acid can induce apoptosis in HTR-8/SVneo cells via overexpression of ERp29 and activation of p38. | |
| BCN6956 | Taspine |
| 1. Taspine can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner. 2. Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo. 3. Taspine has shown meaningful angiogenesis activity . 4. Taspine exhibits a dose-related cicatrizant effect and an ED50 of 0.375 mg/kg. | |
| BCN6957 | Tabernanthine |
| 1. Tabernanthine can decrease morphine and cocaine self-administration in rats, it may be effective in treating addiction to opioid and stimulant drugs. 2. Tabernanthine shows affinity for opiate receptors. 3. In vivo, both tabernanthine and carbolines cause a fine general tremor, suggesting that a possible interaction with benzodiazepine receptors could be involved in the activity of tabernanthine. 4. Tabernanthine tartrate has peripheral cardiovascular effects in anaesthetized rats. | |
| BCN6959 | Sulochrin |
| 1. Sulochrin has an inhibitory activity to eosinophil degranulation. 2. Sulochrin can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytotoxicity up to 50 uM. 3. Sulochrin shows antifungal and antibacterial activities. | |
| BCN6962 | Sudan III |
| 1. C.I. Solvent Red 23, commercial Sudan III, is widely used in cosmetic products. 2. Sudan III dye strongly induces CYP1A1 mRNA expression in HepG2 cells. 3. Sudan III has mutagenic activities. | |
| BCN6963 | Suavioside A |
| 1. Suavioside A tastes sweet, it could be used as a sweetener. | |
| BCN6965 | Strictosidinic acid |
| 1. Strictosidinic acid has a promising effect in the central nervous system. 2. Strictosidinic acid has an antiradical action against DPPH. | |
| BCN6967 | Stachybotrylactam |
| 1. Stachybotrylactam has toxicity. | |
