Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6996 | Sahandol |
| 1. Sahandol shows antiprotozoal activity against P. falciparum and T. brucei rhodesiense. | |
| BCC5310 | Quillaic acid |
| 1. Quillaic acid elicits dose-dependent antinociceptive effects in two murine thermal models. 2. Quillaic acid exhibits strong topical anti-inflammatory activity in both models. | |
| BCC6492 | Sclareolide |
| Sclareolide demonstrates a good antibacterial activity against Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27950, Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212. Sclareolide enhances gemcitabine‑induced cell death through mediating the NICD and Gli1 pathways in gemcitabine‑resistant human pancreatic cancer. | |
| BCN6997 | Scutebarbatine X |
| 1. Scutebarbatine X can inhibit nitric oxide production efficiently with IC50 values of lower than 50 uM, it may have potential effects on the reduction of neuroinflammation. | |
| BCN6999 | Schizandriside |
| 1. Schizandriside and tiliamuroside B shows significant cytotoxicity against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines with inhibitory concentration (IC50) values of 3.26-8.89 uM. 2. Schizandriside may have anti-inflammatory effects, it has inhibitory activities against nitric oxide and prostaglandin E(2) production in IFN-γ- and lipopolysaccharide-stimulated RAW 264.7 cells. | |
| BCN7001 | Praeroside II |
| 1. Praeroside II shows inhibitory activity of NO production in macrophages. | |
| BCN7006 | Norcaesalpinin E |
| 1. Norcaesalpinin E shows antimalarial activity against the malaria parasite Plasmodium falciparum FCR-3/A2 clone in vitro, with an IC50 value of 0.090 microM. | |
| BCN7007 | Sclareol glycol |
| 1. Sclareol glycol (SG) behaves as an anxiogenic, memory-facilitator and perhaps adaptogenic agent, the effects of SG may be mediated by different mechanisms of action (stimulation of adenylate cyclase, interaction with GABA-ergic and dopaminergic transmitter mechanisms). 2. Sclareol glycol shows inhibitory effects on clonidine-induced aggressive behavior, which are realized mainly via its effect on adenylate cyclase and perhaps involving synaptic transmitter action. 3. Sclareol glycol induces changes in core body temperature by interacting with dopamine (DA) receptors and with the second messenger system of 3',5'-AMP in the brain thermoregulatory areas. | |
