Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7103 | Oxyphyllenone A |
| 1. Oxyphyllenone A can inhibit the NO production in lipopolysaccharide-activated macrophages. | |
| BCN7105 | Leucodin |
| 1. Leucodin shows high anti-hypercholesterolemic potential. 2. Leucodin shows a potent inhibitory activity upon the beta-hexosaminidase release from RBL-2H3 cells in a dose-dependent manner with IC50 of 80 microM, it may have anti-allergic activity. | |
| BCN7107 | 8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate |
| 1. 8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. | |
| BCN7108 | 8alpha-Tigloyloxyhirsutinolide 13-O-acetate |
| 1. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 2. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate is active against both cancer cell lines (IC50 = 3.50 microM for HT29 and IC50 = 4.27 microM for HepG2). | |
| BCN7110 | Chartarlactam A |
| 1. Chartarlactam A shows antihyperlipidemic effects in HepG2 cells. | |
| BCN7111 | 8alpha-Hydroxyhirsutinolide |
| 1. 8alpha-Hydroxyhirsutinolide shows anti-inflammatory activity, it inhibits TNF-α-induced NF-κB activity with the IC(50) value of 1.9 uM. | |
| BCN7116 | Eupatoriopicrin |
| 1. Eupatoriopicrin shows anti-trypanosomal activities and cytotoxicity against Trypanosoma brucei rhodesiense. 2. Eupatoriopicrin shows a weak sensitizing capacity in guinea pigs. 3. Eupatoriopicrin-induced DNA damage may play a role in the observed cytotoxicity. | |
| BCN7117 | Bakkenolide Db |
| 1. Bakkenolide Db may have cytotoxicity. | |
