Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2537 - 2544 of 9359 hot products
| Catalog No. | Product Name |
|---|---|
| BCC7095 | SB 205384 |
|
GABA<sub>A</sub> receptor modulator; slows current decay. Potentiates <span class='symbol'>α</span>6, <span class='symbol'>α</span>3 and <span class='symbol'>α</span>5-subunit-containing receptors (EC<sub>50</sub> values are 280, 695 and 730 nM respectively). Displays little effect on receptors containing <span class='symbol'>α</span>1 or <span class='symbol'>α</span>2 subunits.
|
|
| BCC7096 | CGP 7930 |
|
Positive allosteric modulator of GABA<sub>B</sub> receptors. Increases the potency and efficacy of GABA at both native and recombinant GABA<sub>B</sub> receptors (EC<sub>50</sub> values are 5.37 and 4.60<span class='symbol'>μ</span>M respectively) and enhances the inhibitory effect of the agonist L-baclofen in cultured cortical neurons. Reduces operant self-administration of ethanol in alcohol-preferring rats following i.p. administration.
|
|
| BCC7097 | CGP 13501 |
|
Positive allosteric modulator of GABAB receptors, potentiating the effects of GABA at this receptor type.
|
|
| BCC7098 | SDZ 21009 |
|
<span class='symbol'>β</span>-adrenoceptor and 5-HT<sub>1A/1B</sub> receptor antagonist. pK<sub>B</sub>/pA<sub>2</sub> values are 8.3 and 8.0 for 5-HT<sub>1A</sub> and 5-HT<sub>1B</sub> receptors respectively. Centrally active following systemic administration <em>in vivo</em>.
|
|
| BCC7099 | 5-Iodo-A-85380 dihydrochloride |
|
A highly potent and subtype-selective agonist for the <span class='symbol'>α</span>4<span class='symbol'>β</span>2 and <span class='symbol'>α</span>6<span class='symbol'>β</span>2 nicotinic acetylcholine receptors. Activates <span class='symbol'>α</span>-CTx-MII-sensitive and -insensitive components of [<sup>3</sup>H]dopamine release from rat striatal synaptosomes, corresponding to <span class='symbol'>α</span>6<span class='symbol'>β</span>2 and <span class='symbol'>α</span>4<span class='symbol'>β</span>2 (EC<sub>50</sub> values are 12.7 and ~35 nM respectively). ~5000- , 25000- and 140000-fold selective over <span class='symbol'>α</span>3<span class='symbol'>β</span>4, <span class='symbol'>α</span>7 and muscle nAChR receptors respectively. Precursor also available.
|
|
| BCC7100 | Quinelorane hydrochloride |
|
Dopamine D2 and D3 receptor agonist; Ki values are 5.7 and 3.4 nM respectively.
|
|
| BCC7101 | LY 215840 |
|
5-HT2/5-HT7 receptor antagonist. Reduces stimulatory effect of serotonin on aldosterone secretion; also reduces 5-HT-induced cAMP formation (pKB = 8.26).
|
|
| BCC7102 | 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative |
|
Precursor to the highly potent and selective ligand for the <span class='symbol'>α</span>4<span class='symbol'>β</span>2 nicotinic receptor, 5-Iodo-A-85380.Suitable for radioiodination.
|
|