Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2593 - 2600 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7152 | K 252a |
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Non-selective protein kinase inhibitor; analog of staurosporine. Inhibits PKC (IC<sub>50</sub> = 32.9 nM), Ca<sup>2+</sup>/calmodulin-stimulated phosphodiesterases (IC<sub>50</sub> = 1.3 - 2.9 <span class='symbol'>μ</span>M), MLCK (K<sub>i</sub> = 20 nM) and receptor tyrosine kinases. Inhibits the oncogenic properties of MET; prevents autophosphorylation and activation of downstream effectors (MAPK, Akt).
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| BCC7153 | Autocamtide-2-related inhibitory peptide |
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Selective and potent calmodulin-dependent protein kinase II (CaM kinase II) inhibitor (IC<sub>50</sub> = 40 nM). Selective over PKC, PKA and CaM kinase IV (IC<sub>50</sub> > 10 <span class='symbol'>μ</span>M).
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| BCC7154 | SCH 28080 |
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Potent inhibitor of H+,K+-ATPase (IC50 = 20 nM); binds to the K+ recognition site and is competitive with respect to K+. Inhibits gastric acid secretion in vitro and in vivo.
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| BCC7155 | Enoximone |
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Inhibitor of type III phosphodiesterase (PDE3). Increases intracellular cyclic AMP (cAMP) concentrations and enhances myocardial contractility. Also induces concentration-dependent vasodilation in vitro.
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| BCC7156 | L-655,240 |
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Potent and selective thromboxane A2/prostaglandin endoperoxide receptor antagonist. pA2 values are 8 - 8.4 in guinea pig smooth muscle; IC50 = 7 nM for inhibition of human platelet aggregation. Orally active in vivo.
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| BCC7157 | CGS 15943 |
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Potent adenosine receptor antagonist (Ki values are 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors respectively). Orally active in vivo.
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| BCC7158 | BIIE 0246 |
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Potent, selective and competitive non-peptide antagonist for the neuropeptide Y Y<sub>2</sub> receptor (IC<sub>50</sub> = 15 nM). Displays > 650-fold selectivity over Y<sub>1</sub>, Y<sub>4</sub> and Y<sub>5</sub> receptors. Active <em>in vivo</em>.
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| BCC7159 | A 77636 hydrochloride |
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Potent and selective dopamine D1-like receptor agonist (pEC50 values are 8.97 and < 5 for D1-like and D2-like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo.
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