Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2649 - 2656 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7211 | [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P |
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Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. Induces apoptosis and inhibits cancer cell growth in vitro.
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| BCC7212 | DCB |
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Allosteric ligand for the metabotropic glutamate receptor mGlu<sub>5</sub>; displays neutral modulation. Does not affect agonist-stimulated mGlu<sub>5</sub> responses, but blocks regulation of the receptor by other allosteric modulators such as DFB and DMeOB.
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| BCC7213 | DMeOB |
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Negative allosteric modulator of the metabotropic glutamate receptor mGlu<sub>5</sub>; displays reversible non-competitive inhibition of mGlu<sub>5</sub>-mediated responses (IC<sub>50</sub> = 3 <span class='symbol'>μ</span>M).
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| BCC7214 | Ritanserin |
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Potent and long-acting 5-HT2 receptor antagonist (Ki = 0.39 nM). Anxiolytic in vivo.
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| BCC7215 | GR 79236 |
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Adenosine A1 receptor agonist (Ki = 3.1 nM). Anticonvulsive in mice following systemic administration in vivo.
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| BCC7216 | SB 258585 hydrochloride |
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Potent and selective 5-HT6 receptor antagonist (pKi = 8.6); displays > 160-fold selectivity over other 5-HT receptor subtypes.
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| BCC7217 | UCM 707 |
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Potent endocannabinoid transport inhibitor. IC<sub>50</sub> values are 0.8 and 30 <span class='symbol'>μ</span>M for inhibition of the anandamide transporter and FAAH respectively. K<sub>i</sub> values are 4700, 67 and > 5000 nM for CB<sub>1</sub>, CB<sub>2 </sub>and VR1 receptors respectively. Potentiates hypokinetic and antinociceptive effects of anandamide <em>in vivo</em>.
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| BCC7218 | AS 19 |
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Potent 5-HT7 receptor agonist (IC50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia in vivo.
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