Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN4227 | Spathulenol |
| 1. Spathulenol has immunomodulatory effect. 2. Spathulenol shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway. 3. Spathulenol presents moderate or low cytotoxicity with IC50 higher than 6uM, it is a good candidate to be used in combination chemotherapy of MDR cancer and therefore is worthy for further in vivo studies. | |
| BCN4233 | Rediocide C |
| 1. Rediocide C exhibits potent activity against D. pteronyssinus with respective LC50 values of 5.59 microg/cm2. 2. Rediocide C and rediocide G exhibit antimycobacterial activity, with the MIC value of 3.84 uM. | |
| BCN4236 | Martynoside |
| 1. Martynoside has antioxidative activity. 2. Martynoside is a natural selective estrogen receptor modulator. 3. Martynoside has anticancer and antimetastatic activities. 4. Martynoside has the potential of antagonizing sports anaemia, the mechanism of this effect might be related to preventing RBC from free radical damage. 5. Martynoside and verbascoside can resist muscle fatigue, which is depending on their antioxidative activities. | |
| BCN4237 | Trifolirhizin |
| Trifolirhizin possesses potential anti-inflammatory and anti-cancer activities, it inhibits acetylcholine mediated airway smooth muscle (ASM) contraction or directly relaxes pre-contracted ASM independent of β 2 -adrenoceptors. Trifolirhizin may be a a candidate as skin-whitening agents, it exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis. | |
| BCN4238 | 4',5,7-Trihydroxy-6-prenylflavone |
| 1. 6-Prenylapigenin(4',5,7-Trihydroxy-6-prenylflavone) shows potent inhibitory activity on melanin formation, it may be potential sources for skin whitening agents. 2. 6-Prenylapigenin shows moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines. | |
| BCN4239 | Chonglou Saponin VII |
| 1. Chonglou saponin VII shows inhibitory effects on cell proliferation. | |
| BCN4241 | Imbricatolic acid |
| 1. Imbricatolic acid can prevent cell cycle progression in p53-null CaLu-6 cells. | |
| BCN4242 | 6',7'-Dihydroxybergamottin acetonide |
| 1. 6',7'-Dihydroxybergamottin is a potent inhibitor of CYP3A activity, and may be primarily responsible for the effects of grapefruit juice on cytochrome P450 activity in humans. | |
