Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN4271 | Canniprene |
| 1. Canniprene has anti-inflammatory activity, it can potently inhibit the production of inflammatory eicosanoids via the 5-lipoxygenase pathway (IC50=0.4uM) and also can affect the generation of prostaglandins via the cyclooxygenase/microsomal prostaglandin E2 synthase pathway (IC50 =10 uM). | |
| BCN4278 | Laurifoline |
| 1. Laurifoline is a potential NF-κB inhibitor and a potential β2 -adrenegic receptor agonist, it can not only inhibit Pseudomonas aeruginosa PAK strain-induced inflammatory responses via a negative regulation of the Braf protein that participates in MAPK signaling pathway but also activate the β2 -adrenegic receptor. 2. Laurifoline may show anti-HBV activities in vitro using the HBV transfected Hep G2.2.15 cell line. | |
| BCN4280 | Specioside |
| 1. Specioside has analgesic activity. 2. Specioside has anti-dyspeptic and astringent activities. 3. Specioside has liver stimulating and wound healing activities. 4. Specioside exhibits potent antioxidant activity. 5. Specioside ameliorates oxidative stress and promotes longevity in Caenorhabditis elegans. | |
| BCN4282 | Ilicol |
| 1. Pinocembrin and Ilicol inhibit root growth and show IC50 (root growth) values of 0.199, 14.68, 8.05, 7.69 mM, and 1.22, 2.90, 7.35, 8.07 mM, against P. miliaceum, A. sativa, L. sativa, and R. sativus, respectively. 2. Pinocembrin and Ilicol reduce Allium cepa cell division without chromosome aberrations. | |
| BCN4283 | Odorine |
| 1. Odorine has potent anti-carcinogenic effect by inhibiting both the initiation and promotion stages of two-stage skin carcinogenesis. 2. Odorine was found to inhibit the growth of the vinblastine-resistant KB cells by enhancing the anticancer activity of vinblastine. | |
| BCN4284 | Odorinol |
| 1. Odorine and Odorinol inhibit both the initiation and promotion stages of two-stage skin carcinogenesis. 2. (+)-Odorinol exhibits strong antiviral activity against Ranikhet disease virus (RVD) in chick embryo. | |
| BCN4285 | Deoxyartemisinin |
| 1. Deoxyartemisinin can inhibit microbial growth and reproduction,and is therefore likely to influence biochemical reactions in soils. | |
| BCN4288 | 27-p-Coumaroyloxyursolic acid |
| 1. 27-trans-p-Coumaroyloxyursolic acid and 27-cis-p-coumaroyloxyursolic acid show potent inhibitory activity in the acyl CoA cholesteryl acyl transferase (ACAT) assay. | |
