Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2729 - 2736 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7292 | N20C hydrochloride |
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Selective, non-competitive NMDA receptor antagonist (IC<sub>50</sub> = 5 <span class='symbol'>μ</span>M); binds to the receptor-associated ion channel and prevents glutamate-induced Ca<sup>2+</sup> influx. Displays neuroprotective activity <em>in vivo</em>. Brain-penetrant.
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| BCC7293 | ABT 724 trihydrochloride |
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Potent dopamine D<sub>4</sub> receptor partial agonist (EC<sub>50</sub> = 12.4 nM; 61% efficacy vs. dopamine). Has no agonist activity at D<sub>2</sub> receptors (EC<sub>50</sub> > 10 <span class='symbol'>μ</span>M). Selective in rats <em>in vivo</em>; produces penile erection following i.c.v. administration; increases intracavernosal pressure and potentiates the proerectile effects of sildenafil following s.c. administration. Displays minimal side effects.
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| BCC7294 | (±)-HIP-A |
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Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [3H]D-aspartate release (IC50 = 1.6 μM) rather than [3H]L-glutamate uptake (IC50 = 18 μM). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC50 values are 43 and 8 μM respectively). .
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| BCC7295 | (±)-HIP-B |
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Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [<sup>3</sup>H]D-aspartate release (IC<sub>50</sub> = 1.2 <span class='symbol'>μ</span>M) rather than [<sup>3</sup>H]L-glutamate uptake (IC<sub>50</sub> = 16.9 <span class='symbol'>μ</span>M). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC<sub>50</sub> values are 35 and 45 <span class='symbol'>μ</span>M respectively).
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| BCC7296 | FURA-2AM |
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Fluorescent Ca<sup>2+</sup> indicator. Selective for Ca<sup>2+</sup> over other divalent cations Mg<sup>2+</sup>, Zn<sup>2+</sup>, Fe<sup>2+</sup> and Mn<sup>2+</sup>. Used to determine intracellular Ca<sup>2+</sup> concentration.
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| BCC7297 | MNI caged kainic acid |
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Kainic acid caged with the photosensitive 4-methoxy-7-nitroindolinyl group. Generates large inward currents at resting membrane potential upon wide field photolysis in Purkinje neurons.
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| BCC7298 | Flutax 1 |
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A fluorescent taxol derivative that binds to the taxol microtubule binding site with high affinity (K<sub>a</sub> ~ 10<sup>7</sup>M<sup>-1</sup>). Useful for direct imaging of the microtubule cytoskeleton. Excitation maximum ~ 495 nm; emission maximum ~ 520 nm.
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| BCC7299 | CI 976 |
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Selective acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitor (IC<sub>50</sub> = 0.073 <span class='symbol'>μ</span>M). Lowers non-high density lipoprotein (HDL)-cholesterol and increases HDL-cholesterol concentrations in rats with pre-established dyslipidemia. Orally active. Also inhibits Golgi-associated LPL acyltransferase (LPAT) activity (IC<sub>50</sub> = 15 <span class='symbol'>μ</span>M).
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