Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN4369 Picrasidine A
1. Picrasidine A is a kind of reference standards.
BCN4370 Perforatumone
1. Perforatumone may exhibit inhibitory activities against acetylcholinesterase and human tumor cell lines.
BCN1338 3-Oxo-24,25,26,27-tetranortirucall-7-en-23,21-olide
1. 3-Oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone shows significant inhibitory activities against human cancer cell lines in vitro.
BCN1337 Methyl 3-hydroxy-4,5-dimethoxybenzoate
1. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows obvious antimicrobial activities, the minimum inhibitory concentration of it is 5 mg/ml against Staphylococcus aureus and Rhizopus, and 10 mg/ml against E. coli. 2. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows fairly active for oxidation resistance in the presence of H2O2.
BCN4373 Ethyl gallate
Ethyl gallate has anti-cancer, antioxidant activities, it may be an alternative class of vasopressors for use in septic shock. Ethyl gallate can treat acute lung injury (ALI) mainly by reducing the total cells and infiltration of activated polymorphonuclear leukocytes (PMNs). Ethyl gallate inhibits Akt , NF-κB p-65, Bcl-2/Bax, and mRNA levels of MMP-2 and MMP-9.
BCN4376 Stigmasterol
Stigmasterol is used as a precursor in the manufacture of synthetic progesterone, it is an antagonist of the bile acid nuclear receptor FXR, which has anti-inflammatory, thyroid inhibitory, cholesterol-lowering, antiperoxidative and hypoglycemic effects; it has indicated that stigmasterol may be useful in prevention of certain cancers, including ovarian, prostate, breast, and colon cancers. Stigmasterol inhibits the NF-kappaB pathway.
BCN4377 Anisofolin A
1. Anisofolin A has promising antimalarial activity (IC50 4.39 ± 0.25 uM). 2. Anisofolin A has promising antimycobacterium activity [IC50 4.50 ± 0.75 uM (3.31 ug/mL)] against M. tuberculosis H37Ra and at 100 ug/mL, shows 55.6 % inhibition of M. bovis.
BCN4378 Ibogaine
1. Ibogaine has the propensity to prolong the QT interval of the electrocardiogram in humans, may generate life-threatening cardiac arrhythmias . 2. Ibogaine has promising anti-addictive property in animals.