Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2817 - 2824 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7381 | (±)-AC 7954 hydrochloride |
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Highly selective, non-peptide urotensin-II (UT) receptor agonist that displays potent activity at human and rat UT receptors (pEC50 values are 6.5 and 6.7 respectively).
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| BCC7382 | MNITMT |
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Novel, non-toxic immunosuppressive agent. Inhibits human mixed lymphocyte reaction <em>in vitro</em> (ED<sub>50</sub> = 2.7 <span class='symbol'>μ</span>M) and prolongs skin graft survival in mice. Produces a 98.1% reduction in antibody response following oral administration in rabbits.
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| BCC7383 | VUF 5681 dihydrobromide |
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Potent histamine H3 receptor silent antagonist (pKi = 8.35).
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| BCC7384 | VUF 8430 dihydrobromide |
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High affinity (pKi = 7.5), potent histamine H4 receptor full agonist (pEC50 = 7.3). Displays moderate affinity for H3 receptors (pKi = 6.0) and weak partial agonist activity at H2 receptors.
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| BCC7385 | Melperone hydrochloride |
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Atypical neuroleptic; 5-HT<sub>2A</sub>/D<sub>2</sub> receptor antagonist (K<sub>i</sub> values are 120 and 180 nM respectively). Causes an increase in dopamine levels in the medial prefrontal cortex (mPFC) and nucleus accumbens and an increase in ACh in the mPFC. Also binds adrenergic <span class='symbol'>α</span><sub>1</sub> and <span class='symbol'>α</span><sub>2</sub> receptors (K<sub>i</sub> values are 180 and 150 nM respectively).
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| BCC7386 | MRS 2693 trisodium salt |
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Selective P2Y<sub>6</sub> agonist (EC<sub>50</sub> = 0.015 <span class='symbol'>μ</span>M at the hP2Y<sub>6</sub> receptor). Displays no activity at other P2Y subtypes. Exerts a cytoprotective effect in an <em>in vivo</em> mouse model of hindlimb skeletal muscle ischemia/reperfusion injury.
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| BCC7387 | (-)-Bicuculline methiodide |
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Methiodide form of classical GABA<sub>A</sub> receptor antagonist (+)-bicuculline. More water-soluble and stable. Non-GABA receptor-mediated actions reported, including actions on calcium-dependent potassium channels.
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| BCC7388 | Nonactin |
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Monovalent cation ionophore that displays selectivity for K<sup>+</sup> and NH<sub>4</sub><sup>+</sup> (K<sup>+</sup> = NH<sub>4</sub><sup>+</sup> > Na<sup>+</sup> > Mg<sup>2+</sup> > Li<sup>+</sup> >> Ca<sup>2+</sup> for nonactin-EVA sensor). Induces cation transport across artificial membranes. Also inhibits P-glycoprotein-mediated efflux of chemotherapeutic agents in multiple-drug resistant cancer cells. Antibiotic.
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