Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN4497 | Isomartynoside |
| 1. Isomartynoside has inhibition against the angiotensin converting enzyme (ACE) activities, the IC 50 value is 505±26.7μg/ml, it may have antihypertensive effect. 2. Isomartynoside shows obvious anti-fatigue activity. | |
| BCN4498 | Rhuscholide A |
| 1. Rhuscholide A possesses significant anti-HIV-1 activity with an EC50 value of 1.62 microM and a therapeutic index (TI) of 42.40. | |
| BCN4509 | Guajadial |
| 1. Guajadial, psidial A and psiguadials A and B can reduce tumor growth and stimulate uterus proliferation, suggest that they may act as Selective Estrogen Receptors Modulators (SERMs), therefore holding significant potential for anticancer therapy. 2. Guajadial shows α-glucosidase inhibitory activities significantly and its activity was better than that of Acarbose. 3. Guajadial exhibits potent inhibitory effects on the growth of human hepatoma cells. | |
| BCN4512 | Isoliquiritigenin |
| Isoliquiritigenin has hepatoprotective, chemopreventive, antitumor, vasorelaxant, anti-platelet, anti-allergic, antiviral, antioxidant and anti-inflammatory effects, it can induce growth inhibition and apoptosis through downregulating AA metabolic network and the deactivation of PI3K/Akt in human breast cancer. Isoliquiritigenin also has the ability to protect cells from AA+iron-induced H2O2 production and mitochondrial dysfunction, which is mediated with GSK3β phosphorylation downstream of AMPK. | |
| BCN4517 | Artanin |
| 1. Artanin displays promising inhibition against both MSSA and MRSA with minimal inhibitory concentrations (MICs) of 8-64 ug/ml, but very weak against Gram-negative pathogen and yeast with MICs of 256 to ≥1024 ug/ml. | |
| BCN4518 | Hosenkoside M |
| Hosenkoside M is a rare baccharane glycoside from Impatiens balsamina. | |
| BCN4519 | (-)-Epigallocatechin(EGC) |
| (-)-Epigallocatechin exhibits antiplatelet,anticoagulation,anti-tumor,anti-cancer and anti-inflammatory functions. Epigallocatechin activates haem oxygenase-1 expression via protein kinase Cdelta and Nrf2. Cu(2+) with (-)-epigallocatechin (EGC) facilitated DNA cleavage, while Ag+ with EGC showed a strong repressive effect. | |
| BCN4520 | 8-Hydroxy-4-cadinen-3-one |
| 1. 8-Hydroxy-4-cadinen-3-one shows significant inhibitory activity against A.thaliana seedling root growth. | |
