Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2841 - 2848 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7405 | SUN-B 8155 |
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Non-peptide calcitonin (CT) receptor agonist that fully stimulates cAMP production in CHO/hCTR cells (EC<sub>50</sub> = 21 <span class='symbol'>μ</span>M). Causes a significant reduction in serum calcium concentrations <em>in vivo</em> following i.p. administration.
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| BCC7406 | CD 1530 |
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Potent and selective RAR<span class='symbol'>γ</span> receptor agonist (K<sub>i</sub> values are 150, 1500 and 2750 nM for RAR<span class='symbol'>γ</span>, RAR<span class='symbol'>β</span> and RAR<span class='symbol'>α</span> receptors respectively). Activates transcriptional activity (AC<sub>50</sub> = 1.8 nM).
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| BCC7407 | GYKI 53655 hydrochloride |
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Non-competitive AMPA and kainate receptor antagonist. Analog of GYKI 52466. Prolongs the survival time after MgCl<sub>2</sub>- induced global cerebral ischemia. Exhibits anticonvulsant activity. Also blocks GluK3 homomeric receptors (IC<sub>50</sub> = 63 <span class='symbol'>μ</span>M) and GluK2b(R)/GluK3 heteroreceptors (IC<sub>50</sub> = 32 <span class='symbol'>μ</span>M) at high concentrations.
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| BCC7408 | PNU 109291 |
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Potent and selective 5-HT1D receptor agonist that displays > 600-fold selectivity over 5-HT1A and 5-HT2A receptors and no activity at 5-HT1B, 5-HT1E, 5-HT2B, 5-HT2C, 5-HT6 and 5-HT7 receptors. Reduces dural plasma extravasation evoked by trigeminal ganglion stimulation.
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| BCC7409 | 10-DEBC hydrochloride |
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Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 <span class='symbol'>μ</span>M), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC<sub>50</sub> ~ 2-6 <span class='symbol'>μ</span>M) and induces apoptosis in rhabdomyosarcoma cells.
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| BCC7410 | Calmidazolium chloride |
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Calmodulin antagonist. Inhibits calmodulin-dependent phosphodiesterase and Ca<sup>2+</sup>-transporting ATPase with IC<sub>50</sub> values of 0.15 and 0.35 <span class='symbol'>μ</span>M respectively. Also causes elevation of intracellular calcium in HL-60 cells, independent of calmodulin inhibition.
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| BCC7411 | PB 28 dihydrochloride |
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High affinity <span class='symbol'>σ</span><sub>2</sub> receptor agonist (K<sub>i</sub> values are 0.8 and 15.2 nM for <span class='symbol'>σ</span><sub>2</sub> and <span class='symbol'>σ</span><sub>1</sub> receptors respectively) that displays minimal affinity at other receptors. Inhibits electrically evoked twitch in guinea pig bladder and ileum (EC<sub>50</sub> values are 2.62 and 3.96 <span class='symbol'>μ</span>M respectively). Displays antiproliferative and cytotoxic effects in SK-N-SH neuroblastoma and C6 glioma cells.
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| BCC7412 | Fexaramine |
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Potent, selective farnesoid X receptor agonist (EC<sub>50</sub> = 25 nM). Displays no activity at hRXR<span class='symbol'>α</span>, hPPAR<span class='symbol'>α</span>, hPPAR<span class='symbol'>γ</span>, hPPAR<span class='symbol'>δ</span>, mPXR, hPXR, hLXR<span class='symbol'>α</span>, hTR<span class='symbol'>β</span>, hRAR<span class='symbol'>β</span>, mCAR, mERR<span class='symbol'>γ</span> and hVDR receptors.
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