Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN4581 Secologanin dimethyl acetal
1. Secologanin dimethyl acetal induces significant neurite outgrowth.
BCN4582 Isoscopoletin
Isoscopoletin possesses inhibitory activity against hepatitis B virus (HBV) replication; it also shows substantial inhibition against multi-drug resistant CEM/ADR5000 cells and human CCRF-CEM leukaemia cells, with the IC50 value is 1.6 and 4.0 microM, respectively.
BCN4584 Hosenkoside B
Hosenkoside B is a natural product from Impatiens balsamina L.
BCN4585 2'-Hydroxydaidzein
1. 2'-Hydroxygenistein is an isoflavonoid phytoalexin. 2. 2'-Hydroxygenistein suppress chemical mediators in inflammatory cells, may have value in treatment and prevention of central and peripheral inflammatory diseases associated with excess production of chemical mediators. 3. 2'-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase and lysozyme from rat neutrophils in response to formyl-Met-Leu-Phe/cytochalasin B (fMLP/CB) with IC(50) values of 2.8+/-0.1 and 5.9+/-1.4 microM, respectively.
BCN4586 Piptocarphin A
1. Piptocarphin A shows strong cytotoxic activity against mouse lymphoid tumor cell line P388 with the IC(50) value of 0.77 microM .
BCN4587 Derrone
1. Derrone may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens. 2. Derrone is a novel Aurora kinase inhibitor, it can significantly inhibit the formation and growth of MCF7 tumor spheroids.
BCN4588 Broussonin C
1. Broussonin C and broussin are antifungal compounds. 2. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase.
BCN4589 Methyl 3,4,5-trimethoxycinnamate
Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel.