Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2849 - 2856 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7413 | ZK 756326 |
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Selective, non-peptide CCR8 chemokine receptor agonist (IC<sub>50</sub> values are 1.8 and 2.6 <span class='symbol'>μ</span>M for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at <span class='symbol'>α</span><sub>2A</sub> and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.
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| BCC7414 | Melanotan II |
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High affinity melanocortin receptor agonist (Ki values are 0.67, 6.6, 34 and 46 nM for MC1, MC4, MC3 and MC5 receptors respectively). Stimulates erectile activity, inhibits food intake and displays neuroprotective properties in vivo.
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| BCC7415 | Kisspeptin 10 (human) |
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Potent endogenous ligand for the Kisspeptin receptor (KISS1, GPR54). Binds with high affinity to rat and human KISS1 receptors with Ki values of 1.59 and 2.33 nM respectively. Inhibits metastasis and invasion in mouse melanomas and stimulates gonadotropin secretion following i.c.v. administration.
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| BCC7416 | PSB 069 |
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Non-selective nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor. Reported to inhibit rat NTPDases 1, 2 and 3 with similar potencies.
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| BCC7417 | PSB 06126 |
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Nucleoside triphosphate diphosphohydrolase 3 (NTPDase 3) inhibitor. Reported to inhibit rat NTPDase 3 at low micromolar concentrations and display selectivity over NTPDase 1 and NTPDase 2.
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| BCC7418 | Zamifenacin fumarate |
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Selective M3 muscarinic receptor antagonist (pKi values are 8.52, 7.93, 7.90 and 7.78 for M3, M2, M1 and M4 receptors respectively). Displays higher affinity at ileal M3 receptors (pKi = 9.3) compared to oesophageal and tracheal M3 receptors (pKi values are 8.8 and 8.2 respectively). Inhibits gastrointestinal motility in vivo in the absence of cardiovascular effects.
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| BCC7419 | Tenidap |
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NSAID that preferentially inhibits COX-1 (IC<sub>50</sub> values are < 0.03, 1.2 and > 30 <span class='symbol'>μ</span>M for COX-1, COX-2 and 5-lipoxygenase respectively). Inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. Opener of inward rectifying hK<sub>ir</sub>2.3 channel (EC<sub>50</sub> = 402 nM).
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| BCC7420 | α-MSH |
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Endogenous melanocortin receptor agonist (K<sub>i</sub> values are 0.12, 31, 660 and 5700 nM for MC<sub>1</sub>, MC<sub>3</sub>, MC<sub>4</sub> and MC<sub>5</sub> receptors respectively). Anti-inflammatory peptide; antagonizes proinflammatory mediators, including TNF-<span class='symbol'>α</span>, IL-6 and NO and induces anti-inflammatory cytokine IL-10. Inhibits food intake and induces penile erections following i.c.v. administration.
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