Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN4615 | Homopterocarpin |
| 1. Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribute to the antiulcerogenic property of P. erinaceus. 2. Homopterocarpin can inhibit (lower concentration) or kill (higher concntration) human^s liver cancer cells under the cultured condition, they have anticancer activity. 3. Homopterocarpin can contribute to the hepatoprotective and antioxidant potentials of P. erinaceus extract in acetaminophen-provoked hepatotoxicity. 4. (-)-Homopterocarpin has active insect antifeedant against both S. litura and R. speratus. 5. (+)-Homopterocarpin has antimitotic effect. | |
| BCN4617 | Nimbin |
| 1. Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. 2. Nimbin requires to elicit a 50% inhibition of this steroid hydroxylase activity in the three insect species examined ranged from approximately 2 x 10(-5) to 1 x 10(-3). 3. Nimbin shows anti-feedant activity and toxicity against larvae of three species of Lepidoptera, Spodoptera littoralis (Boisd), Spodoptera frugiperda (FE Smith) and Helicoverpa armigera (Hübner) and nymphs of the locusts Schistocerca gregaria (Forskål) and Locusta migratoria (L). | |
| BCN4618 | Isopimaric acid |
| 1. Isopimaric acid is active against MDR and MRSA strains of S. aureus which are becoming increasingly resistant to antibiotics, the minimum inhibitory concentrations (MIC) are 32-64 microg/mL . 2. Isopimaric acid is also possible that an antagonistic interaction with reserpine may render the antibiotics inactive. | |
| BCN4619 | Rhamnocitrin |
| 1. Rhamnocitrin and kaempferol can augment cellular antioxidant defense capacity, at least in part, through regulation of HO-1 expression and MAPK signal transduction. 2. Rhamnocitrin and kaempferol not only protect low-density lipoprotein from oxidation but also prevent atherogenesis through suppressing macrophage uptake of oxidized low-density lipoprotein. 3. Rhamnocitrin can enhance the immune function, improve the formation of spleen cells of mice serum hemolysin of chicken red blood cell immune. 4. Rhamnocitrin shows a significant protection against cloudiness in lenses induced by hydrogen peroxide and hydrocortisone in a dose dependent manner, suggests that rhamnocitrin possesses significant anticataract activity and acts most likely due to its antioxidant property. | |
| BCN4621 | Durantoside I |
| 1. Durantoside I has inhibitory activity on the growth of lettuce seedling. 2. Durantoside I displays DPPH scavenging activity. | |
| BCN4625 | Allamandicin |
| 1. Allamandicin shows antifeedant and insecticidal activities against fifth instar larvae of Pieris rapae larvae , the AFC50 value is 0.045 mg/mL after 48 hours. | |
| BCN4627 | Totarol |
| 1. Totarol has anti-bacteria effect by restraining bacterial growth by perturbing the cell division and proliferation, including several pathogenic Gram-positive bacteria, mycobacterium tuberculosis. 2. Totarol treatment leads to metabolic shutdown by repressing the major central metabolic dehydrogenases in B. subtilis. | |
| BCN4628 | Phytone |
| Phytone appeares to enhance both the sticky materials production and cell growth, suggesting that it plays some role in the increase of sticky materials and cell growth. | |
