Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2945 - 2952 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7510 | TB 21007 |
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GABA<sub>A</sub> receptor inverse agonist selective for the <span class='symbol'>α</span><sub>5</sub>-subtype (K<sub>i</sub> values are 1.6, 16, 20 and 20 nM for <span class='symbol'>α</span>5, <span class='symbol'>α</span>2, <span class='symbol'>α</span>1 and <span class='symbol'>α</span>3 subtypes respectively). Brain penetrant; enhances cognitive performance in rats in the delayed matching-to-place morris water maze test following i.p. administration.
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| BCC7511 | EO 1428 |
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Selective inhibitor of p38<span class='symbol'>α</span> and p38<span class='symbol'>β</span><sub>2</sub> that displays no activity at p38<span class='symbol'>γ</span>, p38<span class='symbol'>δ</span>, ERK1/2 and JNK1. Inhibits production of inflammatory cytokines including IL-8, TNF-<span class='symbol'>α</span>, IL-6, IL-1<span class='symbol'>β</span> and IL-10 (IC<sub>50</sub> values are 4, 5, 17, 30 and 74 nM respectively). Displays anti-inflammatory activity in murine models of acute and chronic dermatitis.
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| BCC7512 | Ro 04-6790 |
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Potent and selective 5-HT<sub>6</sub> receptor antagonist (pK<sub>i</sub> values are 7.26 and 7.35 at rat and human 5-HT<sub>6</sub> receptors respectively). Displays no affinity at a range of other receptors (IC<sub>50</sub> > 10 <span class='symbol'>μ</span>M). Induces stretching behavior in rats <em>in vivo</em>.
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| BCC7513 | Ro 64-5229 |
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Selective, non-competitive mGlu<sub>2</sub> antagonist. Inhibits GTP<span class='symbol'>γ</span><sup>35</sup>S binding to mGlu<sub>2</sub>-containing membranes (IC<sub>50</sub> = 0.11 <span class='symbol'>μ</span>M).
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| BCC7514 | MRS 2690 |
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Potent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.
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| BCC7515 | Veratridine |
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Voltage-gated Na<sup>+</sup> channel opener; increases intracellular Ca<sup>2+</sup> with no effect on the Na<sup>+</sup>/Ca<sup>2+</sup> exchanger. Steroid-derived alkaloid neurotoxin. Increases membrane Na<sup>+</sup> permeability and depolarizes excitable tissues.
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| BCC7516 | NBMPR |
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Equilibrative nucleoside transporter 1 (ENT1) inhibitor (Ki values are 0.4 and 2800 nM for hENT1 and hENT2 respectively).
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| BCC7517 | LP 12 hydrochloride |
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5-HT<sub>7</sub> receptor agonist displaying selectivity over D<sub>2</sub>, 5-HT<sub>1A</sub> and 5-HT<sub>2A</sub> receptors (K<sub>i</sub> values are 0.22, 7.3, 52.7 and 326 nM respectively). Induces relaxation of substance P-induced contractions in guinea pig ileum (EC<sub>50</sub> = 1.77 <span class='symbol'>μ</span>M).
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