Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 2993 - 3000 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7559 | LY 334370 hydrochloride |
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Selective 5-HT<sub>1F</sub> receptor agonist (K<sub>i</sub> values are 1.87, 16.4, > 100 (IC<sub>50</sub>), 176, 189, 281, 1280, 1530, 1550, > 3000 (IC<sub>50</sub>) and 3250 nM for 5-HT<sub>1F</sub>, 5-HT<sub>1A</sub>, 5-HT<sub>4</sub>, 5-HT<sub>1E</sub>, 5-HT<sub>1B</sub>, 5-HT<sub>1D</sub>, 5-HT<sub>2B</sub>, 5-HT<sub>2A</sub>, 5-HT<sub>7</sub>, 5-HT<sub>6</sub> and 5-HT<sub>2C</sub> receptors respectively). Displays antimigraine effects.
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| BCC7560 | DMCM hydrochloride |
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Benzodiazepine inverse agonist that displays anxiogenic and potent convulsant activity.
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| BCC7561 | L-651,582 |
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Orally active Ca<sup>2+</sup> channel blocker; inhibits K<sup>+</sup>- and carbachol-stimulated Ca<sup>2+</sup> influx (IC<sub>50</sub> values are 500 and 935 nM respectively). Exhibits antiproliferative, antiangiogenic and antimetastatic activity <em>in vivo</em> and displays selectivity towards numerous mismatch repair-deficient tumor cell lines <em>in vitro</em>.
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| BCC7562 | CJ 033466 |
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Potent and selective 5-HT<sub>4</sub> partial agonist (EC<sub>50</sub>= 0.927 nM). Displays > 1000-fold selectivity for 5-HT<sub>4</sub> over other 5-HT and D<sub>2</sub> receptors. Exhibits gastroprokinetic effects <em>in vivo</em> following oral administration. Weakly blocks hERG (IC<sub>50</sub> = 2.6 <span class='symbol'>μ</span>M).
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| BCC7563 | Gallein |
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Inhibitor of G protein <span class='symbol'>βγ</span> subunit-dependent signaling. Blocks PI 3-kinase and Rac1 activation in HL60 cells and chemotaxis in HL60 differentiated cells.
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| BCC7564 | FR 236924 |
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Selective PKC<span class='symbol'>ε</span> activator that displays > 7-fold selectivity over other PKC isozymes. Stimulates glutamate release via presynaptic <span class='symbol'>α</span>7 nicotinic receptors on glutamatergic terminals <em>in vitro</em> and enhances cognition <em>in vivo</em>. Brain penetrant.
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| BCC7565 | Pertussis Toxin |
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Bacterial toxin that catalyzes ADP-ribosylation of G-proteins G<sub>i</sub>, G<sub>o</sub> and G<sub>t</sub>. Impairs G protein heterotrimer interaction with receptors, blocking receptor coupling.
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| BCC7566 | GYKI 47261 dihydrochloride |
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Non-competitive AMPA receptor antagonist (IC<sub>50</sub> = 2.5 <span class='symbol'>μ</span>M). Displays broad spectrum anticonvulsive activity and neuroprotective effects <em>in vivo</em>.
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