Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3001 - 3008 of 9359 hot products
| Catalog No. | Product Name |
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| BCC7568 | XRP44X |
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Ras-Net (Elk-3) pathway inhibitor (IC<sub>50</sub> = 10 - 20 nM). Indirectly inhibits Net phosphorylation upstream of Erk1/2 activation. Mediates G<sub>2</sub>-M cell cycle arrest, suppresses growth of multiple cell types (IC<sub>50</sub> ~ 2 nM), inhibits angiogenesis and acts as a microtubule depolymerizing agent <em>in vitro</em>.
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| BCC7569 | (-)-Cotinine |
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Major metabolite of nicotine. Shown to activate a subpopulation of <span class='symbol'>α</span>3/<span class='symbol'>α</span>6<span class='symbol'>β</span>2 nAChRs in monkey striatum. Displays cognition-enhancing effects <em>in vivo</em>; reduces amyloid <span class='symbol'>β</span> (A<span class='symbol'>β</span>) aggregation and improves memory in an Alzheimer's disease mouse model.
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| BCC7570 | UDP disodium salt |
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Endogenous P2Y receptor agonist which preferentially activates P2Y<sub>6</sub>. Shown to be a competitive antagonist at P2Y<sub>14</sub> receptors.
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| BCC7571 | Cyclapolin 9 |
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Selective, ATP-competitive polo-like kinase 1 (PLK1) inhibitor (IC<sub>50</sub> = 500 nM).
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| BCC7572 | BMS CCR2 22 |
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High affinity CCR2 chemokine receptor antagonist (IC<sub>50</sub> = 5.1 nM). Displays potent functional antagonism, IC<sub>50</sub> values are 1 and 18 nM for chemotaxis and antagonism of calcium flux respectively. Selective over CCR3.
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| BCC7573 | NE 100 hydrochloride |
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Potent and selective <span class='symbol'>σ</span><sub>1</sub> receptor antagonist (K<sub>i</sub> = 0.86 nM) that displays > 55-fold selectivity over <span class='symbol'>σ</span><sub>2</sub> receptors and > 6000-fold selectivity over D<sub>1</sub>, D<sub>2</sub>, 5-HT<sub>1A</sub>, 5-HT<sub>2</sub> and PCP receptors. Exhibits reversible binding (K<sub>d</sub> = 1.2 nM) and displays antipsychotic activity <em>in vivo</em>. Orally active.
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| BCC7574 | PHA 568487 |
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Agonist of the <span class='symbol'>α</span>7 nicotinic acetylcholine receptor (K<sub>i</sub> values are 44 and 2800 for <span class='symbol'>α</span>7 and 5-HT<sub>3</sub> respectively, IC<sub>50</sub> values are > 100 <span class='symbol'>μ</span>M for <span class='symbol'>α</span>3<span class='symbol'>β</span>4 and <span class='symbol'>α</span>1<span class='symbol'>β</span>1<span class='symbol'>δ</span><span class='symbol'>γ</span> respectively, and % inhibition is < 1 and 5% for <span class='symbol'>α</span>4<span class='symbol'>β</span>2 and hERG respectively). Orally active and brain penetrant.
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| BCC7575 | 2-Chloroadenosine |
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Metabolically stable analog of adenosine that behaves as an adenosine receptor agonist (K<sub>i</sub> values are 300, 80 and 1900 nM for A<sub>1</sub>, A<sub>2A</sub> and A<sub>3</sub> receptors respectively). Anticonvulsive <em>in vivo</em>.
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