Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN4812 Pseudoakuammigine
1. Pseudoakuammigine exhibits opioid analgesic activity in vivo. 2. Pseudoakuammigine exhibits anti-inflammatory and analgesic actions, the analgesic actions are mediated via interaction with opioid receptors.
BCN4815 (-)-Variabilin
1. Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3. 2. Variabilin is an inhibitor of human secretory and cytosolic phospholipase A2 (PLA2) activities that controls eicosanoid production in vitro and in vivo, inhibits neutrophil degranulation and superoxide generation in vitro and shows anti-inflammatory activity after topical or p.o. administration to mice. 3. Variabilin is an antimicrobial furanosesterterpene. 4. Variabilin is an important chemotaxonomic marker for the family Irciniidae.
BCN4816 Phaseollin
1. Phaseollin and neorautenol may be responsible for the anticarcinogenic actions of the plant extract, may lead to new pharmacons to be used in cancer therapy. 2. 9-Aminoacridine and other DNA intercalators function as inducers of Phaseollin and phenylalanine ammonia lyase synthesis by reacting with the DNA template. 3. The red kidney bean phytoalexins kievitone and phaseollin possess both estrogenic and antiestrogenic activities.
BCN4817 Neolitsine
1. Neolitsine exhibits EC90 values (concentration at which 90% loss of larval motility is observed) of 6.4 microg/mL. 2. Neolitsine and dicentrine have potent vasorelaxing effects on precontracted rat aortic preparations with mean IC 50 values between 0.08 and 2.48 microM.
BCN4818 Piperolactam C
1. Piperolactam C can inhibit the growth of the fungi Cladosporium sphaerospermum and C. cladosporioides. 2. Piperolactam C possesses anti-platelet aggregation activity in vitro.
BCN4819 Maltol
Maltol is a naturally occurring organic compound that is flavour enhancer and flavouring agent. Maltol has neuroprotective effects against hypoxia-induced neuroretinal cell damage in R28 cells, and it has potential as a new neuroprotective therapeutic agent for oxidative stress-related ocular diseases, including glaucoma.Maltol exhibits hepatoprotective effect on alcohol-induced liver oxidative injury, may due to its potent antioxidant properties.
BCN4820 2-Hydroxynaringenin
1. The recombinant protein exhibits high FNS I activity catalyzing the conversion of naringenin to apigenin and 2-Hydroxynaringenin.
BCN4827 4'-O-Methyllicoflavanone
1. 4'-O-Methyllicoflavanone shows cytotoxic properties against P-388 cells, with the IC 50 value of 17.98 ug/mL.